Fox H, Puehler T, Schulz U, Bitter T, Horstkotte D, Oldenburg O
Department of Cardiology, Heart and Diabetes Center North Rhine, Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany.
Department of Cardiology, Heart and Diabetes Center North Rhine, Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany.
Transplant Proc. 2014 Sep;46(7):2462-3. doi: 10.1016/j.transproceed.2014.06.063.
Sleep-disordered breathing (SDB), especially central sleep apnea with Cheyne-Stokes respiration (CSA-CSR), is highly prevalent in patients with severe heart failure (HF). SDB, and predominantly CSR, may improve after recovery of cardiac function, but available data are limited and inconclusive, particularly in patients who have undergone heart transplantation (HTX).
The case of a 59-year-old man with dilated cardiomyopathy and advanced chronic HF, plus CSA-CSR, is reported. The patient showed normalization of cardiac function after successful HTX, with delayed but gradual stepwise improvements in CSA-CSR over time.
Although there is a close relationship between cardiac function and manifestations of SDB and CSA-CSR, stabilization of nocturnal respiration after improvement in cardiac function may be delayed rather than immediate.
睡眠呼吸障碍(SDB),尤其是伴有陈-施呼吸的中枢性睡眠呼吸暂停(CSA-CSR),在重度心力衰竭(HF)患者中非常普遍。心脏功能恢复后,SDB,尤其是CSR,可能会有所改善,但现有数据有限且尚无定论,特别是在接受心脏移植(HTX)的患者中。
报告了一名59岁男性患者,患有扩张型心肌病和晚期慢性心力衰竭,伴有CSA-CSR。患者在成功进行HTX后心脏功能恢复正常,CSA-CSR随时间逐渐延迟但逐步改善。
虽然心脏功能与SDB和CSA-CSR的表现之间存在密切关系,但心脏功能改善后夜间呼吸的稳定可能会延迟而非立即出现。