Capozi G, Gavina G
Clin Ter. 1989 Mar 31;128(6):423-7.
Forty years after it was first described, diphenylhydantoin-induced gum hypertrophy has still not found an explanation of its pathophysiologic mechanism. The authors review the incidence, modes of onset and possible pathogenetic factors of this side effect and stress local hygiene as the most effective means of provention, so far.
在首次被描述40年后,苯妥英钠引起的牙龈增生仍未找到其病理生理机制的解释。作者回顾了这种副作用的发生率、发病方式和可能的致病因素,并强调局部卫生是迄今为止最有效的预防手段。