Ortiz-Ortiz Karen J, Ortiz-Martínez de Andino José J, Torres-Cintrón Carlos R, Tirado-Gómez Maribel, González-Falero Andrea, Caballero-Varona Daniela, Ortiz Ana Patricia, Pérez-Ríos Naydi
P R Health Sci J. 2014 Sep;33(3):132-5.
In Puerto Rico, leukemia is among the top 10 cancers in terms of incidence and mortality. The aim of the study described herein was to establish the overall leukemia survival rate in Puerto Rico and determine whether there are differences in leukemia survival by type of health insurance coverage.
Data for adult patients (aged > or = 20 years) diagnosed with leukemia were provided by the Puerto Rico Central Cancer Registry. The relative survival rates (1, 3, and 5 years) were estimated for leukemia patients (diagnosed from 2004 through 2006) by type of health insurance (government health plan [GHP] or non-government health plan [NGHP]). Relative survival is defined as observed survival in the cohort divided by expected survival in the cohort. A Poisson regression model was used to analyze the relative excess risk of death for both the GHP and the NGHP groups.
A total of 516 leukemia patients were eligible for analysis. The overall survival rates of leukemia patients in PR for 1, 3, and 5 years after diagnosis were 55.8%, 40.5%, and 34.7%, respectively. Relative survival rates were lower for patients with GHP (1 year = 52.8%; 3 years = 36.4%; 5 years = 32.2%) than they were in people with NGHP (1 year = 57.5%; 3 years = 42.8%; 5 years = 36.1%). Among patients aged 65+ years, those with GHP had a 1.58-fold (95% CI: 1.11-2.27) higher risk of death than did those patients with NGHP.
Several factors could explain the disparities observed in leukemia survival rates (as grouped by health insurance status) in PR. Some of them include differences in patterns of healthcare coverage, in delays in treatment, in quality of service, in risk factors, and co-morbidities present in the older population studied.
在波多黎各,白血病在发病率和死亡率方面位列十大癌症之中。本文所述研究的目的是确定波多黎各白血病的总体生存率,并确定按医疗保险覆盖类型划分的白血病生存率是否存在差异。
波多黎各中央癌症登记处提供了成年白血病患者(年龄≥20岁)的数据。按医疗保险类型(政府医疗计划[GHP]或非政府医疗计划[NGHP])估算了白血病患者(2004年至2006年确诊)的相对生存率(1年、3年和5年)。相对生存率定义为队列中的观察生存率除以队列中的预期生存率。使用泊松回归模型分析GHP组和NGHP组的相对超额死亡风险。
共有516名白血病患者符合分析条件。波多黎各白血病患者诊断后1年、3年和5年的总体生存率分别为55.8%、40.5%和34.7%。GHP患者的相对生存率(1年=52.8%;3年=36.4%;5年=32.2%)低于NGHP患者(1年=57.5%;3年=42.8%;5年=36.1%)。在65岁及以上的患者中,GHP患者的死亡风险比NGHP患者高1.58倍(95%CI:1.11 - 2.27)。
有几个因素可以解释在波多黎各观察到的白血病生存率差异(按医疗保险状况分组)。其中一些因素包括医疗覆盖模式的差异、治疗延迟、服务质量、风险因素以及所研究老年人群中存在的合并症。