Naoumova Julia, Kurol Jüri, Kjellberg Heidrun
Department of Orthodontics, Institute of Odontology at the Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden
Department of Orthodontics, Institute of Odontology at the Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.
Eur J Orthod. 2015 Apr;37(2):209-18. doi: 10.1093/ejo/cju040. Epub 2014 Sep 22.
To analyse whether extraction of the deciduous canines facilitates eruption of the palatal displaced canines (PDCs), and to analyse root resorption in adjacent teeth caused by the PDCs.
Eligibility criteria for participants were as follows: children at age 10-13 years with either maxillary unilateral or bilateral PDC, persisting deciduous canine and no previous experience of orthodontic treatment. Sixty-seven patients (40 girls and 27 boys; age: mean ± standard deviation: 11.4±1.0) with unilateral (45) or bilateral (22) PDCs were consecutively recruited and randomly allocated using permuted block randomization method to extraction or non-extraction. No patients dropped out after the randomization or during the study. Patients underwent a clinical examination and cone beam computed tomography at baseline (T0), after 6 (T1) and 12 months (T2). The total observation time was 24 months. Outcome measures were eruption, positional changes, length of time until eruption, and root resorption of adjacent teeth. The baseline images were measured blinded while the 6- and 12-month control images were not, since it was not possible to blind the extracted canine.
Significantly more spontaneous eruptions of the PDCs were seen in the extraction group (EG) than in the control group (CG), with rates of 69 and 39 per cent, respectively, with a mean eruption time of 15.6±5.6 months in the EG and 18.8±5.8 months in the CG. Significant differences in changes between the groups, in favour of the EG, were found for all variables except for the sagittal angle. In the EG, the changes in the distances of the canine cusp-tip were larger during the first 6 months, while the change of apex was larger between 6 and 12 months. There were no significant differences in resorption of adjacent teeth between the groups.
Imputation values were used for the PDCs who had erupted at T2, since no x-rays were taken for ethical reasons, which might have given uncertainty in the positional changes between T1 and T2.
Extraction of the deciduous canine is an effective treatment in patients with PDCs. Significantly more positional changes and shorter mean eruption time were seen in the EG. Resorptions of lateral incisors were seen in both groups, but none exceeded grade 2 (resorption up to half of the dentine thickness to the pulp).
This trial was registered in "FoU i Sverige" (http://www.fou.nu/is/sverige), registration number: 40921.
The protocol was not published before trial commencement.
分析拔除乳尖牙是否有助于腭侧异位尖牙(PDC)的萌出,并分析PDC对相邻牙齿牙根吸收的影响。
研究对象的纳入标准如下:年龄在10 - 13岁,患有上颌单侧或双侧PDC,乳牙尖牙仍存留且既往无正畸治疗史。连续招募67例单侧(45例)或双侧(22例)PDC患者,采用排列分组随机化方法随机分为拔牙组和非拔牙组。随机分组后及研究期间无患者退出。患者在基线(T0)、6个月(T1)和12个月(T2)时接受临床检查和锥形束计算机断层扫描。总观察时间为24个月。观察指标包括萌出情况、位置变化、萌出所需时间以及相邻牙齿的牙根吸收情况。基线图像测量时采用盲法,而6个月和12个月的对照图像测量时未采用盲法,因为无法对已拔除的尖牙进行盲法处理。
拔牙组(EG)中PDC的自发萌出明显多于对照组(CG),发生率分别为69%和39%,EG组的平均萌出时间为15.6±5.6个月,CG组为18.8±5.8个月。除矢状角外,所有变量在两组间的变化均存在显著差异,且均有利于EG组。在EG组中,尖牙牙尖距离在前6个月变化较大,而根尖在6至12个月间变化较大。两组间相邻牙齿的吸收情况无显著差异。
由于伦理原因,T2时已萌出的PDC未拍摄X线片,因此使用了推算值,这可能导致T1和T2之间位置变化存在不确定性。
拔除乳尖牙是治疗PDC患者的有效方法。EG组的位置变化明显更多,平均萌出时间更短。两组均观察到侧切牙牙根吸收,但均未超过2级(吸收至牙本质厚度达牙髓的一半)。
本试验在“瑞典的FoU”(http://www.fou.nu/is/sverige)注册,注册号:40921。
研究方案在试验开始前未发表。