Hong Sung-Hee, Anu Davaasuren, Jeong Young-Il, Abmed Davaajav, Cho Shin-Hyeong, Lee Won-Ja, Lee Sang-Eun
Division of Malaria & Parasitic Diseases, Korea National Institute of Health, Korea Centers for Disease Control and Prevention, Osong 363-951, Korea.
Laboratory of Parasitology, National Center for Communicable Diseases, Ministry of Health, Ulaanbaator-210648, Mongolia.
Korean J Parasitol. 2014 Aug;52(4):443-7. doi: 10.3347/kjp.2014.52.4.443. Epub 2014 Aug 29.
Babesiosis is an emerging tick-borne disease in humans worldwide; however, little is known about the frequency of infection or prevalence of this disease in other parts of the world, excluding North America. In this study, we aimed to investigate Babesia microti infection frequency in a human population in Mongolia. One hundred blood samples were collected from stock farmers living in Khutul city of Selenge province, Mongolia. The sera and DNA from blood samples were evaluated for the presence of B. microti infection by using indirect fluorescent antibody (IFA) tests and PCR. The positive detection rates obtained using the IFA tests and PCR assays were 7% and 3%, respectively. This study is the first to detect of B. microti infections based on antibody seroprevalence or PCR assays for the presence of B. microti DNA in a Mongolian population.
巴贝斯虫病是一种在全球范围内新出现的人兽共患蜱传疾病;然而,除北美外,对于世界其他地区该疾病的感染频率或流行情况知之甚少。在本研究中,我们旨在调查蒙古人群中巴贝斯虫微小种的感染频率。从生活在蒙古色楞格省胡图勒市的牧民中采集了100份血样。通过间接荧光抗体(IFA)试验和聚合酶链反应(PCR)对血样中的血清和DNA进行评估,以检测微小巴贝斯虫感染情况。IFA试验和PCR检测的阳性检出率分别为7%和3%。本研究首次基于抗体血清阳性率或用于检测微小巴贝斯虫DNA的PCR检测,在蒙古人群中检测到微小巴贝斯虫感染。