Department of Neuroscience, Unit of Neurorehabilitation, University Hospital of Pisa, Pisa, Italy.
NeuroRehabilitation. 2014;35(3):509-18. doi: 10.3233/NRE-141144.
Exercise is well tolerated and induces relevant improvements in physical and mental functioning of persons with Multiple Sclerosis (MS). Unfortunately, due to the wide variety of symptoms and the broad range of exercise interventions, it is not possible to make unified exercise recommendation as to what type of exercise is safe and effective for persons with MS.
The aim was to test the impact of an intensive task-oriented training on motor function and quality of life in 17 MS patients with an Expanded Disability Status Scale (EDSS) between 4 and 5.5.
Patients underwent a two-week intensive, task-oriented rehabilitation program. Outcome measures were: Berg Balance Scale, Gait Dynamic Index, 6 Minute Walking Test, Physiological Cost Index, Fatigue Severity Scale, 10 metres Walking Test, Timed Up and Go test, Short form 36, Multiple Sclerosis Impact Scale, Patient Health Questionnaire.
All outcome measures showed a significant improvement after the treatment except for the 6 Minute Walking test and the Short form 36 that showed a trend of improvement although not statistically significant.
An intensive task-oriented rehabilitation protocol is effective in improving motor function and has a positive impact on quality of life in MS patients with moderate disability.
运动在多发性硬化症(MS)患者中耐受性良好,并能显著改善其身心机能。不幸的是,由于症状种类繁多,运动干预范围广泛,因此无法针对何种类型的运动对 MS 患者既安全又有效做出统一的运动建议。
本研究旨在测试针对 EDSS 评分为 4 至 5.5 的 17 名 MS 患者进行为期两周的强化、以任务为导向的康复训练对运动功能和生活质量的影响。
患者接受了为期两周的强化、以任务为导向的康复计划。评估指标包括 Berg 平衡量表、步态动力学指数、6 分钟步行测试、生理成本指数、疲劳严重程度量表、10 米步行测试、起立-行走计时测试、SF-36 量表、多发性硬化症影响量表、患者健康问卷。
除 6 分钟步行测试和 SF-36 量表外,所有评估指标在治疗后均有显著改善,虽然后者的改善趋势虽不具有统计学意义。
强化、以任务为导向的康复方案可有效改善 MS 中度残疾患者的运动功能,并对其生活质量产生积极影响。