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[急慢性肝病患者体内的循环免疫复合物]

[Circulating immune complexes in patients with acute and chronic diseases of the liver].

作者信息

Uibo R M, Nutt H R, Prjukk T J

出版信息

Ter Arkh. 1989;61(2):61-4.

PMID:2524905
Abstract

Altogether 471 persons were examined. Of these, 370 suffered from acute and chronic liver diseases and 101 were normal. 75 persons were examined over time (in the course of one year). The measurements were made of IgG-circulating immune complexes (CICs) and of CICs containing specific liver lipoprotein. It was established that IgG-CICs were mostly detectable in patients with acute viral hepatitis B, autoimmune chronic active hepatitis, and with primary biliary cirrhosis. CICs containing specific liver protein were detectable more frequently in patients with autoimmune chronic hepatitis and alcohol-induced liver injury.

摘要

总共对471人进行了检查。其中,370人患有急慢性肝病,101人正常。75人接受了为期一年的随访检查。检测了循环免疫球蛋白G免疫复合物(CIC)以及含有特异性肝脂蛋白的CIC。结果发现,在急性乙型病毒性肝炎、自身免疫性慢性活动性肝炎和原发性胆汁性肝硬化患者中,大多能检测到免疫球蛋白G - CIC。在自身免疫性慢性肝炎和酒精性肝损伤患者中,含有特异性肝蛋白的CIC更常被检测到。

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