Maekawa Takanobu, Oba Mari S, Katsunuma Toshio, Ishiguro Akira, Ohya Yukihiro, Nakamura Hidefumi
Department of General Pediatrics and Interdisciplinary Medicine, National Center for Child Health and Development, Tokyo, Japan.
Department of Biostatistics and Epidemiology, Graduate School of Medicine, Yokohama City University, Kanagawa, Japan.
Allergol Int. 2014 Dec;63(4):603-7. doi: 10.2332/allergolint.13-OA-0681.
The Modified Pulmonary Index Score (MPIS) was developed as an indicator of the severity of acute asthma in children. The objective of this study is to evaluate the reliability and validity of the MPIS for children with acute asthma, including those five years or younger in age.
We evaluated the inter-rater reliability and internal consistency of the MPIS by having at least two trained physicians and a nurse-each of whom was blinded to the others' scores-simultaneously examine inpatients with asthma exacerbation and rate them according to the MPIS. We also evaluated the intraclass correlation coefficient (ICC), kappa, Cronbach's α and correlations between the MPIS and other indicators associated with asthma severity.
A total of 25 children (median age, five years; 13 patients were five years or younger in age) were enrolled in this study. The MPIS showed excellent inter-rater reliability (all ages: ICC = 0.95, 95% CI = 0.94-0.97; five years or younger: ICC = 0.93, 95% CI = 0.89-0.96) and good internal consistency (all ages: Cronbach's α = 0.87; five years or younger: Cronbach's α = 0.85). The MPIS showed good correlation with a visual analogue scale assessed by the physicians.
The MPIS was a sufficiently reliable assessment tool for children with acute asthma, including those five years or younger in age.
改良肺指数评分（MPIS）被开发作为儿童急性哮喘严重程度的一个指标。本研究的目的是评估MPIS在急性哮喘儿童中的可靠性和有效性，包括5岁及以下的儿童。
我们通过让至少两名经过培训的医生和一名护士（他们对彼此的评分均不知情）同时检查哮喘急性加重的住院患者并根据MPIS对他们进行评分，来评估MPIS的评分者间信度和内部一致性。我们还评估了组内相关系数（ICC）、kappa值、克朗巴哈系数α以及MPIS与其他哮喘严重程度相关指标之间的相关性。
本研究共纳入25名儿童（中位年龄为5岁；13名患者年龄为5岁及以下）。MPIS显示出优异的评分者间信度（所有年龄：ICC = 0.95，95% CI = 0.94 - 0.97；5岁及以下：ICC = 0.93，95% CI = 0.89 - 0.96）和良好的内部一致性（所有年龄：克朗巴哈系数α = 0.87；5岁及以下：克朗巴哈系数α = 0.85）。MPIS与医生评估的视觉模拟量表显示出良好的相关性。
MPIS是用于急性哮喘儿童（包括5岁及以下儿童）的一个足够可靠的评估工具。
