分子和血清学快速检测作为哥斯达黎加犬类克氏锥虫感染的标志物
Molecular and serological rapid tests as markers of Trypanosoma cruzi infection in dogs in Costa Rica.
作者信息
Lizundia Regina, Picado Albert, Cordero Marlen, Calderón Alejandra, Deborggraeve Stijn, Montenegro Victor M, Urbina Andrea
机构信息
Department of Pathology and Infectious Diseases, Royal Veterinary College, University of London, Hatfield, United Kingdom.
Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium ; Barcelona Centre for International Health Research (CRESIB, Hospital Clínic Universitat de Barcelona), Barcelona, Spain.
出版信息
Trop Parasitol. 2014 Jul;4(2):111-4. doi: 10.4103/2229-5070.138539.
INTRODUCTION
Chagas disease is a zoonotic disease caused by Trypanosoma cruzi and dogs are one of the main domestic reservoirs.
MATERIALS AND METHODS
One molecular (OligoC-TesT, Coris Bioconcept) and one serological (T. cruzi-Detect, Inbios) rapid tests were evaluated as infection markers for T. cruzi in 102 dogs living in eight villages endemic for Chagas in Costa Rica.
RESULTS
T. cruzi-Detect performed well as screening tool with 23.3% positive samples. The large number of invalid results (66.7%) observed in samples tested with OligoC-TesT precluded assessing the use of this new method as epidemiological tool to detect T. cruzi infection in dogs.
引言
恰加斯病是一种由克氏锥虫引起的人畜共患病，狗是主要的家养宿主之一。
材料与方法
对102只生活在哥斯达黎加8个恰加斯病流行村庄的狗，评估了一种分子快速检测法（OligoC-TesT，Coris Bioconcept公司）和一种血清学快速检测法（克氏锥虫检测法，Inbios公司）作为克氏锥虫感染标志物的情况。
结果
克氏锥虫检测法作为筛查工具表现良好，阳性样本率为23.3%。在用OligoC-TesT检测的样本中观察到大量无效结果（66.7%），这使得无法评估将这种新方法用作检测狗身上克氏锥虫感染的流行病学工具的用途。
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