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通过充气导管系统和充水导管系统同时测量的尿动力学压力的转换。

Conversion of urodynamic pressures measured simultaneously by air-charged and water-filled catheter systems.

作者信息

Awada Hassan K, Fletter Paul C, Zaszczurynski Paul J, Cooper Mitchell A, Damaser Margot S

机构信息

Department of Biomedical Engineering, The Cleveland Clinic, Cleveland, Ohio.

Advanced Platform Technology Center, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio.

出版信息

Neurourol Urodyn. 2015 Aug;34(6):507-12. doi: 10.1002/nau.22633. Epub 2014 Sep 22.

Abstract

AIMS

The objective of this study was to compare the simultaneous responses of water-filled (WFC) and air-charged (ACC) catheters during simulated urodynamic pressures and develop an algorithm to convert peak pressures measured using an ACC to those measured by a WFC.

METHODS

Examples of cough leak point pressure and valsalva leak point pressure data (n = 4) were obtained from the literature, digitized, and modified in amplitude and duration to create a set of simulated data that ranged in amplitude from 15 to 220 cm H2 O (n = 25) and duration from 0.1 to 3.0 sec (n = 25) for each original signal. Simulated pressure signals were recorded simultaneously by WFCs, ACCs, and a reference transducer in a specially designed pressure chamber. Peak pressure and time to peak pressure were calculated for each simulated pressure signal and were used to develop an algorithm to convert peak pressures recorded with ACCs to corresponding peak pressures recorded with WFCs. The algorithm was validated with additional simulated urodynamic pressure signals and additional catheters that had not been utilized to develop the algorithm.

RESULTS

ACCs significantly underestimated peak pressures of more rapidly changing pressures, as in coughs, compared to those measured by WFCs. The algorithm corrected 90% of peak pressures measured by ACCs to within 5% of those measured by WFCs when simultaneously exposed to the same pressure signals.

CONCLUSIONS

The developed algorithm can be used to convert rapidly changing urodynamic pressures, such as cough leak point pressure, obtained using ACC systems to corresponding values expected from WFC systems.

摘要

目的

本研究的目的是比较在模拟尿动力学压力下充水导管(WFC)和充气导管(ACC)的同步反应,并开发一种算法,将使用ACC测量的峰值压力转换为WFC测量的峰值压力。

方法

从文献中获取咳嗽漏点压力和瓦尔萨尔瓦漏点压力数据的示例(n = 4),进行数字化处理,并在幅度和持续时间上进行修改,以创建一组模拟数据,每个原始信号的幅度范围为15至220 cm H2O(n = 25),持续时间为0.1至3.0秒(n = 25)。模拟压力信号由WFC、ACC和专门设计的压力室中的参考换能器同时记录。计算每个模拟压力信号的峰值压力和达到峰值压力的时间,并用于开发一种算法,将ACC记录的峰值压力转换为WFC记录的相应峰值压力。该算法用未用于开发该算法的额外模拟尿动力学压力信号和额外导管进行了验证。

结果

与WFC测量的相比,ACC显著低估了如咳嗽时变化更快的压力的峰值压力。当同时暴露于相同压力信号时,该算法将ACC测量的90%的峰值压力校正到WFC测量值的5%以内。

结论

所开发的算法可用于将使用ACC系统获得的快速变化的尿动力学压力,如咳嗽漏点压力,转换为WFC系统预期的相应值。

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