Qu Shao-Hui, Hsiung Ming-Chon, Leng Xiao-Ping, Wei Jeng, Du Guo-Qing, Houle Helene, Yin Wei-Hsian, Tian Jia-Wei
Department of Ultrasound, Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Division of Cardiology, Heart Center, Cheng Hsin General Hospital, Taipei, Taiwan.
Echocardiography. 2015 Jun;32(6):983-92. doi: 10.1111/echo.12748. Epub 2014 Sep 23.
To observe the geometric changes in aortic-mitral valve coupling (AMC) on three-dimensional transesophageal echocardiography and the factors leading to decreased mitral regurgitation (MR) after coronary artery bypass grafting (CABG).
This study included 23 patients undergoing CABG for coronary artery disease. Fifteen patients with moderate to severe MR were separately analyzed to determine whether the severity of MR influences the geometric change in AMC. Echocardiographic examinations were performed pre- and post-CABG, and the studied parameters were obtained using Siemens Auto Valve Analysis software. The effective mitral regurgitant orifice area, left ventricular ejection fraction (LVEF), end-diastolic volume (EDV), and end-systolic volume (ESV) were measured pre- and post-CABG using Philips QLAB software. Ischemic MR, EDV, and ESV significantly decreased (all P < 0.05) and LVEF significantly improved (P < 0.05) after CABG. There were no significant differences between the pre- and post-CABG mitral valve (MV) parameters, aortic valve parameters, aortic-mitral annular angle, or centroid distance (all P > 0.05). Patients with moderate to severe MR exhibited the same results.
The results of this study show that CABG does not cause an acute change in the geometry of AMC. Improved left ventricular function might increase the closing force of the MV, leading to decreased MR after CABG alone. MR significantly improved after CABG alone without MV treatment in the present study. This result may help to guide surgeons in choosing the optimal surgical methods for individual patients.
通过三维经食管超声心动图观察冠状动脉旁路移植术(CABG)后主动脉-二尖瓣连接(AMC)的几何形态变化以及导致二尖瓣反流(MR)减少的因素。
本研究纳入23例因冠状动脉疾病接受CABG的患者。对15例中重度MR患者分别进行分析,以确定MR的严重程度是否影响AMC的几何形态变化。在CABG术前和术后进行超声心动图检查,并使用西门子自动瓣膜分析软件获取研究参数。使用飞利浦QLAB软件测量CABG术前和术后的有效二尖瓣反流口面积、左心室射血分数(LVEF)、舒张末期容积(EDV)和收缩末期容积(ESV)。CABG术后,缺血性MR、EDV和ESV显著降低(均P<0.05),LVEF显著改善(P<0.05)。CABG术前和术后的二尖瓣(MV)参数、主动脉瓣参数、主动脉-二尖瓣环角度或质心距离之间无显著差异(均P>0.05)。中重度MR患者也呈现相同结果。
本研究结果表明,CABG不会引起AMC几何形态的急性变化。左心室功能改善可能会增加MV的关闭力,从而导致单纯CABG术后MR减少。在本研究中,单纯CABG术后未进行MV处理时MR显著改善。这一结果可能有助于指导外科医生为个体患者选择最佳手术方法。