Ibebuogu Uzoma N, Khouzam Rami N, Sharma Gyanendra, Thornton John W, Robati Roshanak, Silverman David
At the University of Tennessee Health Science Center in Memphis, Uzoma N. Ibebuogu is an assistant professor and Rami N. Khouzam is an associate professor. At Georgia Regents University in Augusta, Gyanendra Sharma and John W. Thornton practice in the Division of Cardiology, Roshanak Robati practices in the School of Medicine, and David Silverman practices in the Department of Medicine. The authors have disclosed no potential conflicts of interest, financial or otherwise.
JAAPA. 2014 Oct;27(10):32-5. doi: 10.1097/01.JAA.0000446233.16049.01.
Patent foramen ovale (PFO) is a congenital heart defect that may first be diagnosed in adulthood and has a prevalence of 25% to 30%. Although many patients with PFO are asymptomatic and do not require treatment, paradoxical embolism can cause stroke or myocardial infarction. The authors report an unusual case of PFO with a transversing thrombus in an 80-year-old man. The patient's initial presentation appeared clinically as acute coronary syndrome, but he was subsequently diagnosed with a massive thrombus in transit via a PFO and pulmonary embolus leading to right-sided heart failure.
卵圆孔未闭（PFO）是一种先天性心脏缺陷，可能在成年期首次被诊断出来，患病率为25%至30%。虽然许多卵圆孔未闭患者没有症状，不需要治疗，但反常栓塞可导致中风或心肌梗死。作者报告了一例罕见的80岁男性卵圆孔未闭合并横向血栓形成的病例。患者最初临床表现为急性冠状动脉综合征，但随后被诊断为通过卵圆孔未闭有大量移行血栓及肺栓塞，导致右侧心力衰竭。
