Hellström-Westas Lena, Boylan Geraldine, Ågren Johan
Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Acta Paediatr. 2015 Feb;104(2):123-9. doi: 10.1111/apa.12812. Epub 2014 Oct 22.
There is a lack of scientific evidence to support the best management of neonatal seizures. Current strategies for neonatal seizure management were investigated by analysis of all surveys published during the time period 2000-2012. Methods for seizure diagnosis and availability of electroencephalogram (EEG), including monitoring, varied. Phenobarbital was the drug of first choice, and the use of off-label drugs and treatment times varied.
We conclude that there is an urgent need for more evidence-based studies to guide neonatal seizure management.
缺乏科学证据来支持新生儿惊厥的最佳管理方法。通过分析2000年至2012年期间发表的所有调查,对当前新生儿惊厥管理策略进行了研究。惊厥诊断方法以及脑电图(EEG)的可用性,包括监测情况,各不相同。苯巴比妥是首选药物,非标签药物的使用和治疗时间也各不相同。
我们得出结论,迫切需要更多基于证据的研究来指导新生儿惊厥的管理。