Harbourne Regina, Becker Katherine, Arpin David J, Wilson Tony W, Kurz Max J
Department of Physical Therapy, Munroe-Meyer Institute (Drs Harbourne and Kurz and Mr Arpin), Center for Magnetoencephalography (Ms Becker), and Department of Pharmacology and Experimental Medicine, College of Medicine (Dr Wilson), University of Nebraska Medical Center, Omaha, Nebraska.
Pediatr Phys Ther. 2014 Winter;26(4):462-8. doi: 10.1097/PEP.0000000000000092.
Children who receive treatment for medulloblastoma have a high survival rate, but also a high likelihood of developing posterior fossa syndrome, a condition that includes devastating balance and motor problems. This case series used 2 novel neuromodulation devices in conjunction with an intensive physical therapy intervention for 2 children who were 5 years post tumor treatment with a diagnosis of posterior fossa syndrome. Pre- and postclinical measures, in addition to magnetoencephalography brain imaging, describe positive behavioral and neuroplastic changes resulting from the intervention. The positive outcomes in these cases suggest that further study is needed using neuromodulatory devices and long-term rehabilitation in children with balance and movement disorders resulting from cancer treatment.
接受髓母细胞瘤治疗的儿童生存率较高,但发生后颅窝综合征的可能性也很高,这种病症包括严重的平衡和运动问题。本病例系列对2名肿瘤治疗后5年被诊断为后颅窝综合征的儿童,使用了2种新型神经调节装置,并结合强化物理治疗干预。除了脑磁图脑成像外,临床前后测量结果描述了干预所带来的积极行为和神经可塑性变化。这些病例的积极结果表明,对于因癌症治疗导致平衡和运动障碍的儿童,需要使用神经调节装置和长期康复进行进一步研究。