Irene Petersen, PhD, Department of Primary Care and Population Health, University College London, London; Stephen Evans, MSc, Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London; Irwin Nazareth, PhD, Department of Primary Care and Population Health, University College London, London, UK.
Br J Psychiatry. 2014 Aug;205(2):105-6. doi: 10.1192/bjp.bp.113.141721. Epub 2014 Aug 1.
In this issue, El Marroun et al suggest an association between prenatal selective serotonin reuptake inhibitor (SSRI) exposure and autistic traits in children, as well as an association with prenatal depressive symptoms. However, SSRIs may be mere markers of severity of underlying illnesses and it may be premature to reach such conclusions about effects of treatment. Studies like this raise concerns as this may fuel further anxiety and guilt among women who are faced with depression in pregnancy and possibly leave some women without treatment.
在本期中，El Marroun 等人提出，产前选择性 5-羟色胺再摄取抑制剂（SSRIs）暴露与儿童自闭症特征以及产前抑郁症状之间存在关联。然而，SSRIs 可能仅仅是潜在疾病严重程度的标志物，因此对于治疗效果得出这样的结论还为时过早。像这样的研究引起了人们的关注，因为这可能会进一步加剧怀孕期抑郁症女性的焦虑和内疚感，并且可能导致一些女性得不到治疗。
