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在流感项目-监测疫苗效力(I-MOVE)中开展的流感及其他呼吸道病毒检测

Detection of Influenza and Other Respiratory Viruses Carried Out in the Influenza Project - Monitoring Vaccine Effectiveness (I-MOVE).

作者信息

Woźniak-Kosek Agnieszka

机构信息

Department of Influenza Research, National Influenza Center, National Institute of Public Health-National Institute of Hygiene, 24 Chocimska St., 00-791, Warsaw, Poland,

出版信息

Adv Exp Med Biol. 2015;836:29-33. doi: 10.1007/5584_2014_31.

DOI:10.1007/5584_2014_31
PMID:25252895
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7121447/
Abstract

The project Influenza Vaccine Effectiveness-Monitoring (I-MOVE) is part of the European research carried out by the ECDC (European Center for Disease Prevention and Control), aimed at monitoring the effectiveness of vaccination in Europe during the growing incidence of flu and influenza-like illnesses in the coming epidemic seasons. Laboratory studies using molecular RT-PCR biology methods for detection of genetic material of influenza virus and other respiratory viruses were performed by Voivodeship Sanitary-Epidemiological Stations in Poland. The validation of the results of swabs taken from the nose and throat were carried out in the Department of Influenza Research, National Influenza Center in Warsaw. The study involved 210 samples from patients across Poland. Positive results were recorded for 72.4 % of the samples; influenza virus type A was detected in 43 and type B in 38 cases, whereas in 71 cases other respiratory viruses were detected, which included Human parainfluenza virus type 1-4; Human respiratory syncytial virus type A and B; Human coronavirus 229E/NL63, OC43; Human rhinovirus type A, B, and C; Human enterovirus; and Human adenovirus. The results show that although influenza viruses predominated in the 2010/2011 season in Poland, other flu-like viruses also abounded.

摘要

流感疫苗有效性监测(I-MOVE)项目是欧洲疾病预防控制中心(ECDC)开展的欧洲研究的一部分,旨在监测在即将到来的流行季节流感和流感样疾病发病率不断上升期间欧洲疫苗接种的有效性。波兰省卫生防疫站采用分子逆转录聚合酶链反应生物学方法对流感病毒和其他呼吸道病毒的遗传物质进行检测,开展了实验室研究。取自鼻腔和咽喉的拭子检测结果在华沙国家流感中心流感研究部进行了验证。该研究涉及来自波兰各地患者的210份样本。72.4%的样本检测结果呈阳性;43例检测出甲型流感病毒,38例检测出乙型流感病毒,71例检测出其他呼吸道病毒,包括1-4型人副流感病毒;A、B型人呼吸道合胞病毒;229E/NL63、OC43型人冠状病毒;A、B、C型人鼻病毒;人肠道病毒;以及人腺病毒。结果表明,尽管2010/2011年波兰流感季节流感病毒占主导地位,但其他流感样病毒也大量存在。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a06/7121447/ac682f8039d4/328044_1_En_31_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a06/7121447/b49b7e9dbadd/328044_1_En_31_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a06/7121447/ac682f8039d4/328044_1_En_31_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a06/7121447/b49b7e9dbadd/328044_1_En_31_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a06/7121447/ac682f8039d4/328044_1_En_31_Fig2_HTML.jpg

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本文引用的文献

1
Virological monitoring of influenza activity and influenza-like illness in the epidemic season 2011-2012 in Poland.2011-2012 年流行季波兰流感活动和流感样疾病的病毒学监测。
Adv Exp Med Biol. 2013;788:77-82. doi: 10.1007/978-94-007-6627-3_12.
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Accuracy of rapid influenza detection test in diagnosis of influenza A and B viruses in children less than 59 months old.快速流感检测试验在诊断 59 个月以下儿童甲型和乙型流感病毒中的准确性。
Adv Exp Med Biol. 2013;788:71-6. doi: 10.1007/978-94-007-6627-3_11.
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Influenza diagnosis and vaccination in Poland.
波兰的流感诊断和疫苗接种。
Respir Physiol Neurobiol. 2013 Jun 1;187(1):88-93. doi: 10.1016/j.resp.2013.02.008. Epub 2013 Feb 16.
4
I-MOVE multi-centre case control study 2010-11: overall and stratified estimates of influenza vaccine effectiveness in Europe.I-MOVE 多中心病例对照研究 2010-11 年:欧洲流感疫苗效力的总体和分层估计。
PLoS One. 2011;6(11):e27622. doi: 10.1371/journal.pone.0027622. Epub 2011 Nov 15.