Erbel R, Schatz R, Dietz U, Nixdorff U, Haude M, Aichinger S, Pop T, Meyer J
Versicherungsmedizin. 1989 May 1;41(3):82-4.
To avoid acute complications and restenosis after percutaneous transluminal coronary angioplasty coronary stents were developed. For the first time in 2 patients with severe lesions of the left anterior descending coronary artery 3 Palmaz-Schatz stents were implanted after application and fixation by balloon inflation. The vessels showed larger diameters with smoother surface and smaller gradients compared to balloon angioplasty as related to a blockade of the elastic properties of the vessel and suggested fixation of intima or media dissection. The implantation of the coronary stents was without complications. The control after 24 hours showed an open vessel with unchanged diameter. The patients were without symptoms during control after 4 weeks. Based on this and previous work the implantation of coronary stents seems to open a new dimension for percutaneous transluminal coronary angioplasty because vessel occlusions are prevented and restenosis possibly reduced. The newly designed stents show elementary constructive alternatives to currently used types.
为避免经皮腔内冠状动脉成形术后的急性并发症和再狭窄,冠状动脉支架应运而生。首次在2例左前降支冠状动脉严重病变患者中,通过球囊扩张应用并固定后植入了3枚帕尔马兹-沙茨支架。与球囊血管成形术相比,这些血管直径更大,表面更光滑,梯度更小,这与血管弹性特性的阻断有关,提示内膜或中膜夹层固定。冠状动脉支架植入无并发症。24小时后复查显示血管通畅,直径未变。4周后复查时患者无症状。基于此项及之前的工作,冠状动脉支架植入似乎为经皮腔内冠状动脉成形术开辟了一个新领域,因为可预防血管闭塞并可能减少再狭窄。新设计的支架显示出与当前使用类型不同的基本结构选择。