斑点追踪超声心动图评估2型糖尿病合并冠状动脉粥样硬化患者左心室心肌功能
[Evaluation of left ventricular myocardial function in coronary atherosclerosis patients with type 2 diabetes mellitus by speckle tracking echocardiography].
作者信息
Zhang Lei, Xu Dong, Duan Fujian, Wang Wugang, Jiao Weiping, Yang Yanhui
机构信息
Department of Cardiac Center, Xuanwu Hospital Affiliated to Capital Medical University, Beijing 100053, China.
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出版信息
Zhonghua Yi Xue Za Zhi. 2014 Jul 1;94(25):1973-5.
OBJECTIVE
To evaluate the left ventricular (LV) myocardial function in coronary atherosclerosis patients with type 2 diabetes mellitus (DM) by two-dimensional speckle tracking echocardiography (2D STE).
METHODS
A total of 60 patients with a diagnosis of coronary atherosclerosis (<50%) were divided into DM and non-DM groups (n = 30 each). And another 30 cases were selected as normal control group. LV regional longitudinal, circumferential and radial peak systolic strain (ε) were measured respectively.
RESULTS
EF showed no difference among 3 groups. However the peak systolic longitudinal strain (ε) in LV basal segments, middle segments and apical segments were significantly lower in DM group than those in non-DM and control groups (P < 0.05). The peak systolic circumferential and radial strain parameters showed no significant difference among 3 groups.
CONCLUSION
The systolic longitudinal myocardial function of LV become compromised before reduced LV global systolic function in coronary atherosclerosis patients with type 2 diabetes mellitus.
目的
采用二维斑点追踪超声心动图（2D-STE）评估2型糖尿病（DM）合并冠状动脉粥样硬化患者的左心室（LV）心肌功能。
方法
选取60例诊断为冠状动脉粥样硬化（<50%）的患者，分为糖尿病组和非糖尿病组，每组30例。另选取30例作为正常对照组。分别测量左心室局部纵向、圆周和径向峰值收缩期应变（ε）。
结果
三组间射血分数（EF）无差异。然而，糖尿病组左心室基底段、中间段和心尖段的峰值收缩期纵向应变（ε）显著低于非糖尿病组和对照组（P<0.05）。三组间峰值收缩期圆周和径向应变参数无显著差异。
结论
2型糖尿病合并冠状动脉粥样硬化患者，左心室收缩期纵向心肌功能在左心室整体收缩功能降低之前就已受损。
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