Yanmei Zhong, Yifan Feng, Xia Wu, Jiao Guo
a Central Laboratory, Guangdong Pharmaceutical University , Guangzhou 510006 , P.R. China.
Nat Prod Res. 2015;29(1):53-8. doi: 10.1080/14786419.2014.957700. Epub 2014 Sep 25.
Coumarins is a kind of important components in traditional Chinese medicine. Due to their special structure, they have significant pathological connections with many diseases. In this research, we established a rapid method to analyse the coumarins from Fructus citri Sarcodactylis by using the technique of ultra-performance liquid chromatography with quadruple time-of-flight mass spectrometry. Twenty-one coumarins were identified from Fructus citri Sarcodactylis, 10 were discovered for the first time. At the same time, a rapid sensitive method for identifying coumarins from Fructus citri Sarcodactylis was established.
香豆素类是中药中的一类重要成分。由于其特殊结构,它们与许多疾病有着重要的病理联系。在本研究中,我们建立了一种快速分析佛手香豆素类成分的方法,采用超高效液相色谱-四极杆飞行时间质谱联用技术。从佛手中共鉴定出21种香豆素类成分,其中10种为首次发现。同时,建立了一种快速灵敏的鉴定佛手香豆素类成分的方法。