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基于超高效液相色谱/四极杆飞行时间质谱联用技术快速鉴定化橘红中的香豆素类成分

Rapid identification of coumarins from Fructus citri Sarcodactylis by UPLC/Q-TOF-MS.

作者信息

Yanmei Zhong, Yifan Feng, Xia Wu, Jiao Guo

机构信息

a Central Laboratory, Guangdong Pharmaceutical University , Guangzhou 510006 , P.R. China.

出版信息

Nat Prod Res. 2015;29(1):53-8. doi: 10.1080/14786419.2014.957700. Epub 2014 Sep 25.

DOI:10.1080/14786419.2014.957700
PMID:25253205
Abstract

Coumarins is a kind of important components in traditional Chinese medicine. Due to their special structure, they have significant pathological connections with many diseases. In this research, we established a rapid method to analyse the coumarins from Fructus citri Sarcodactylis by using the technique of ultra-performance liquid chromatography with quadruple time-of-flight mass spectrometry. Twenty-one coumarins were identified from Fructus citri Sarcodactylis, 10 were discovered for the first time. At the same time, a rapid sensitive method for identifying coumarins from Fructus citri Sarcodactylis was established.

摘要

香豆素类是中药中的一类重要成分。由于其特殊结构,它们与许多疾病有着重要的病理联系。在本研究中,我们建立了一种快速分析佛手香豆素类成分的方法,采用超高效液相色谱-四极杆飞行时间质谱联用技术。从佛手中共鉴定出21种香豆素类成分,其中10种为首次发现。同时,建立了一种快速灵敏的鉴定佛手香豆素类成分的方法。

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