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经皮腔内冠状动脉成形术后冠状动脉再狭窄的影响及时间进程。1、2、3、4和5个月时的定量血管造影分析

[Effects and chronology of coronary restenosis after percutaneous transluminal coronary angioplasty. Quantitative angiographic analysis at 1, 2, 3, 4 and 5 months].

作者信息

Koning R, Luijten H E, Beatt K J, Leborgne O, Suryapranata H, van den Brand M, de Feyter P J, Serruys P W

机构信息

Erasmus University, Department of cardiology, Rotterdam, The Netherlands.

出版信息

Arch Mal Coeur Vaiss. 1989 Feb;82(2):177-84.

PMID:2525369
Abstract

Coronary restenosis occurs fairly early after transluminal coronary angioplasty, as suggested by anatomico-clinical, isotopic and angiographic studies. Its incidence, as reported in the literature, varies according to the clinical selection of patients, to the number of patients with follow-up angiography and the timing of this procedure, and to the criteria used to define restenosis. In this prospective study we endeavoured to determine the exact date at which restenosis takes place, as well as its true incidence, by means of 6 different angiographic criteria. The population studied was divided into five groups and each group underwent coronary arteriography at a different date: during the 1st, 2nd, 3rd, 4th and 5th post-angioplasty months respectively. In 424 of the 500 patients thus examined (84.8 p. 100), coronary angiography involved automatic detection of contours and made quantitative analysis possible. Coronary restenosis was found to occur early, with a peak of incidence in the 3rd month. Its incidence varied considerably depending on the criterion used. A critical analysis of the data has prompted us to use a criterion based on absolute values determined by quantitative angiographic analysis.

摘要

解剖临床、同位素及血管造影研究表明,冠状动脉再狭窄在经皮腔内冠状动脉成形术后较早出现。据文献报道,其发生率因患者的临床选择、接受随访血管造影的患者数量及该操作的时机,以及用于定义再狭窄的标准而异。在这项前瞻性研究中,我们试图通过6种不同的血管造影标准来确定再狭窄发生的确切日期及其真实发生率。所研究的人群分为五组,每组在不同日期接受冠状动脉造影:分别在血管成形术后第1、2、3、4和5个月。在接受检查的500例患者中的424例(84.8%)中,冠状动脉造影涉及轮廓的自动检测并使得定量分析成为可能。发现冠状动脉再狭窄较早出现,在第3个月发生率达到峰值。其发生率根据所使用的标准有很大差异。对数据的批判性分析促使我们采用基于定量血管造影分析确定的绝对值的标准。

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