Regional Department for Eating Disorders, Division of Mental Health and Addiction, Oslo University Hospital, Ullevål HF, Oslo, Norway ; Department of Psychiatry, Centre for Research on Eating Disorders at Oxford (CREDO), University of Oxford, Warneford Hospital, Oxford, UK.
Regional Department for Eating Disorders, Division of Mental Health and Addiction, Oslo University Hospital, Ullevål HF, Oslo, Norway ; Division of Mental Health and Addiction, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
J Eat Disord. 2014 Sep 10;2(1):26. doi: 10.1186/s40337-014-0026-y. eCollection 2014.
To systematically review studies of cognitive remediation therapy (CRT) for anorexia nervosa (AN), and to discuss findings with references to clinical practice and future research.
The literature was reviewed using the PubMed, Web of Science and PsycINFO search terms "cognitive remediation therapy" AND "anorexia nervosa". Papers published online between 2005 and 2013 were selected on the basis of three inclusion criteria: 1) studies of any design focusing on CRT for AN, 2) papers that were written in English or had an available published English translation, and 3) papers published in peer reviewed journals.
A total of 45 papers were identified of which 21 were recognized as being relevant for the review. Relevant papers were divided into three different categories 1) single case reports, 2) case series and 3) randomised controlled trials (RCTs). Single case studies and case series yielded strong evidence of feasibility and acceptability of CRT for AN despite great variety in sample compositions. Four RCTs demonstrate that CRT has the potential of enhancing the effectiveness of current treatments, reduce attrition, increase cognitive set-shifting abilities and quality of life, as well as reduce eating disorder psychopathology.
The number of CRT studies published is growing rapidly, in particular RCTs. Further research is needed to define the primary aim of delivering CRT to patients with eating disorders, and to establish how to best measure the effect of the intervention. Moreover, researchers and clinicians should focus on identifying and assessing specific versus non-specific CRT contributions, and explore long-term effects of the intervention. It is imperative that adolescent RCTs are conducted to evaluate how CRT may be effective as a treatment for this young patient group.
系统地回顾认知矫正治疗（CRT）对厌食症（AN）的研究，并结合临床实践和未来研究讨论研究结果。
使用 PubMed、Web of Science 和 PsycINFO 搜索词“认知矫正治疗”和“厌食症”检索文献。根据三个纳入标准选择 2005 年至 2013 年在线发表的论文：1）任何设计都侧重于 CRT 治疗 AN 的研究，2）以英文发表或有英文出版翻译的论文，3）发表在同行评审期刊上的论文。
共确定了 45 篇论文，其中 21 篇被认为与综述相关。相关论文分为三类：1）单个病例报告，2）病例系列，3）随机对照试验（RCT）。尽管样本组成差异很大，但单一病例研究和病例系列研究为 CRT 治疗 AN 的可行性和可接受性提供了强有力的证据。四项 RCT 表明，CRT 有可能增强当前治疗的效果，减少脱落率，提高认知转换能力和生活质量，减少饮食障碍的病理。
发表的 CRT 研究数量增长迅速，特别是 RCT。需要进一步研究来确定向饮食障碍患者提供 CRT 的主要目的，并确定如何最好地衡量干预措施的效果。此外，研究人员和临床医生应专注于确定和评估特定与非特定 CRT 贡献，并探索干预的长期效果。开展青少年 RCT 以评估 CRT 如何作为治疗这一年轻患者群体的有效方法至关重要。
