Spanò G M, Barletta R, Fiorentino E, De Pedrini P, Meloni F, Rapisarda R, Transi M G
Clin Ter. 1989 Apr 15;129(1):17-23.
The authors describe a case of family leukemia: an acute myeloid leukemia preceded by Pelger's anomaly in a 77 year old brother and a chronic myeloid leukemia chromosome Ph + in a 71 years old sister, sixteen years after the first one. The authors formulate a hypothesis that both haematologic diseases may have in common a mistake of transcription caused by an anomalous m RNA.
一名77岁的男性患急性髓细胞白血病，之前存在Pelger异常；16年后，其71岁的姐姐患慢性髓细胞白血病，费城染色体呈阳性。作者提出一个假说，即这两种血液系统疾病可能都存在由异常信使核糖核酸导致的转录错误。
