Raviolo P, Galvagno G, Biarese V, Lovisetto P
Clin Ter. 1989 Apr 15;129(1):31-41.
Diphosphonates are compounds characterized by a P-C-P bond. They are thus analogs of pyrophosphate and can be useful for treating several bone diseases. The authors synthetically review the mechanism of action of these drugs and their most important clinical applications. The authors finally mention the interesting therapeutic possibilities deriving from the development of new members of this class.
双膦酸盐是一类以P-C-P键为特征的化合物。因此,它们是焦磷酸盐的类似物,可用于治疗多种骨病。作者综合回顾了这些药物的作用机制及其最重要的临床应用。作者最后提到了这一类新成员的开发所带来的有趣治疗可能性。