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中等收入环境下的创伤、创伤后应激障碍及精神疾病:患病率与共病情况

Trauma, post-traumatic stress disorder and psychiatric disorders in a middle-income setting: prevalence and comorbidity.

作者信息

Dorrington Sarah, Zavos Helena, Ball Harriet, McGuffin Peter, Rijsdijk Fruhling, Siribaddana Sisira, Sumathipala Athula, Hotopf Matthew

机构信息

Sarah Dorrington, Department of Psychological Medicine, Institute of Psychiatry, King's College London, UK; Helena Zavos, PhD, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, UK; Harriet Ball, PhD, BMBCh, Faculty of Medicine, Imperial College London, UK; Peter McGuffin, PhD, Fruhling Rijsdijk, PhD, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, UK; Sisira Siribaddana, MBBS, MD, Department of Medicine Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, and Institute of Research and Development Sri Lanka; Athula Sumathipala, MD, PhD, Research Institute for Primary Care and Health Sciences, Keele University, and Department of Health Service and Population Research, King's College London Honorary Director, and Institute for Research and Development Sri Lanka; Matthew Hotopf, PhD, Department of Psychological Medicine, Institute of Psychiatry, King's College London, UK.

出版信息

Br J Psychiatry. 2014 Nov;205(5):383-9. doi: 10.1192/bjp.bp.113.141796. Epub 2014 Sep 25.

Abstract

BACKGROUND

Most studies of post-traumatic stress disorder (PTSD) in low- and middle-income countries (LMICs) have focused on 'high-risk' populations defined by exposure to trauma.

AIMS

To estimate the prevalence of post-traumatic stress disorder (PTSD) in a LMIC, the conditional probability of PTSD given a traumatic event and the strength of associations between traumatic events and other psychiatric disorders.

METHOD

Our sample contained a mix of 3995 twins and 2019 non-twins. We asked participants about nine different traumatic exposures, including the category 'other', but excluding sexual trauma.

RESULTS

Traumatic events were reported by 36.3% of participants and lifetime PTSD was present in 2.0%. Prevalence of non-PTSD lifetime diagnosis was 19.1%. Of people who had experienced three or more traumatic events, 13.3% had lifetime PTSD and 40.4% had a non-PTSD psychiatric diagnosis.

CONCLUSIONS

Despite high rates of exposure to trauma, this population had lower rates of PTSD than high-income populations, although the prevalence might have been slightly affected by the exclusion of sexual trauma. There are high rates of non-PTSD diagnoses associated with trauma exposure that could be considered in interventions for trauma-exposed populations. Our findings suggest that there is no unique relationship between traumatic experiences and the specific symptomatology of PTSD.

摘要

背景

大多数关于低收入和中等收入国家(LMICs)创伤后应激障碍(PTSD)的研究都集中在因遭受创伤而定义的“高风险”人群上。

目的

估计一个低收入和中等收入国家创伤后应激障碍(PTSD)的患病率、创伤事件发生后PTSD的条件概率以及创伤事件与其他精神障碍之间关联的强度。

方法

我们的样本包括3995对双胞胎和2019名非双胞胎。我们询问了参与者九种不同的创伤暴露情况,包括“其他”类别,但不包括性创伤。

结果

36.3%的参与者报告有创伤事件,终生患PTSD的比例为2.0%。非PTSD终生诊断的患病率为19.1%。在经历过三次或更多创伤事件的人群中,13.3%有终生PTSD,40.4%有非PTSD精神诊断。

结论

尽管创伤暴露率很高,但该人群的PTSD患病率低于高收入人群,不过患病率可能因排除性创伤而受到轻微影响。与创伤暴露相关的非PTSD诊断率很高,在针对创伤暴露人群的干预措施中应予以考虑。我们的研究结果表明,创伤经历与PTSD的特定症状之间没有独特的关系。

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