四联体分析在小鼠中。
Tetrad analysis in the mouse.
机构信息
Stowers Institute for Medical Research, Kansas City, Missouri, USA, and the Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas, USA.
出版信息
Nat Genet. 2014 Oct;46(10):1045-6. doi: 10.1038/ng.3104.
DOI:10.1038/ng.3104
PMID:25257082
Abstract
Meiotic tetrad analysis is a powerful tool for analyzing all four products of a single meiosis. A new method for tetrad analysis in mammals provides valuable insights into the mechanisms that mediate the exchange of DNA sequences between homologs during meiosis and their influence on the evolution of recombination hotspots.
摘要
减数分裂四联体分析是分析单个减数分裂的所有四个产物的有力工具。哺乳动物中四联体分析的一种新方法为研究介导同源染色体间 DNA 序列交换的机制以及这些机制对重组热点进化的影响提供了有价值的见解。
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