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[不稳定型心绞痛的早期血管成形术。60例连续患者的结果]

[Early angioplasty in unstable angina. Results apropos of 60 consecutive patients].

作者信息

Dubois-Randé J L, Geschwind H, Tavolaro O, Duval A M, Lellouche D, Roudot F, Castaigne A

机构信息

Service de cardiologie du Pr Vernant, CHU Henri-Mondor, Créteil.

出版信息

Arch Mal Coeur Vaiss. 1989 Apr;82(4):517-22.

PMID:2525899
Abstract

Transluminal coronary angioplasty (TCA) is an attractive means of suppressing ischaemia in patients (pts) with unstable angina. Sixty consecutive pts underwent TCA 6 +/- 2.5 days on average after their admission. Only the ischaemic vessel was dilated (mean stenosis 79 p. 100). Primary success was obtained in 53 pts (88 p. 100) with 31 p. 100 of residual stenosis after TCA. Two pts underwent emergency surgery for extensive dissection; failure of traversing the stenotic segment occurred in 2 pts; 3 pts had myocardial infarction (MI) less than 1 h after TCA, 2 arteries have been recanalized by intracoronary streptokinase with persistence of a satisfactory result of TCA, the 3rd patient had occlusion of a secondary side branch. During their stay in hospital, 2 pts had coronary bypass for recurrent angina. After a follow-up period of 6 to 16 months (mean 10 months) early recurrence of angina was observed in a number of cases (before the sixth month in 7 pts). One pt developed MI during the fourth month. At six month, 10 or the initial 60 pts had undergone coronary bypass, 1 undilated pt was asymptomatic; out of 49 dilated pts (47 with one single TCA), 39 were symptom-free but 6 had a positive exercise test, 7 pts were in class II and one in class IV. At control coronary arteriography (46 pts) restenosis was present in 39 p. 100: 5 new TCA and 2 aorto-coronary bypasses were performed. At one year 28 pts had been followed up: 1 was in class IV and 1 in class II, the others being asymptomatic.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

经腔冠状动脉血管成形术(TCA)是抑制不稳定型心绞痛患者缺血的一种有吸引力的方法。连续60例患者在入院后平均6±2.5天接受了TCA。仅对缺血血管进行扩张(平均狭窄率79%)。53例患者(88%)获得了初步成功,TCA后残余狭窄率为31%。2例患者因广泛夹层而接受急诊手术;2例患者未能穿过狭窄段;3例患者在TCA后不到1小时发生心肌梗死(MI),2条动脉通过冠状动脉内链激酶再通,TCA结果良好,第3例患者二级侧支闭塞。住院期间,2例患者因复发性心绞痛接受了冠状动脉搭桥术。在6至16个月(平均10个月)的随访期内,观察到一些病例心绞痛早期复发(7例在第六个月之前)。1例患者在第四个月发生MI。六个月时,最初60例患者中有10例接受了冠状动脉搭桥术,1例未扩张的患者无症状;在49例扩张的患者中(47例接受单次TCA),39例无症状,但6例运动试验阳性,7例患者为II级,1例为IV级。在对照冠状动脉造影(46例患者)中,39%存在再狭窄:进行了5次新的TCA和2次主动脉冠状动脉搭桥术。一年时,对28例患者进行了随访:1例为IV级,1例为II级,其他患者无症状。(摘要截断于250字)

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