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端口型完全植入式中心静脉导管:其在癌症患者治疗中使用引起的并发症

Totally implantable central venous catheters of the port-a-cath type: complications due to its use in the treatment of cancer patients.

作者信息

Granic Miroslav, Zdravkovic Darko, Krstajic Sandra, Kostic Sanja, Simic Aleksandar, Sarac Momir, Ivanovic Nebojsa, Radovanovic Dragan, Dikic Srdjan, Kovcin Vladimir

机构信息

University Medical Center "Bezanijska Kosa", Department of Surgical Oncology, Belgrade;

出版信息

J BUON. 2014 Jul-Sep;19(3):842-6.

Abstract

PURPOSE

A multidisciplinary approach to the treatment of patients with malignant diseases requires adequate venous access in order to safely administer chemotherapy, blood transfusion and blood products, antibiotics, rehydratation and total parenteral nutrition. The insertion of the central venous catheter (CVC), its use and its maintenance can be accompanied by multiple complications.

METHODS

Fifty cancer patients were retrospectively enrolled in this study. The obligatory inclusion criterion was an implanted CVC of the port-a-cath type, inserted for chemotherapy administration. This study included patients who had their catheters inserted in the period from 2001 to 2012.

RESULTS

The median patient age was 44 years (range 28- 68). Thirty five patients (70%) were female and 15 (30%) male. The port-a-cath had been used from 1 to 40 months (16.8 ± 9 months on average). Breast cancer was the most frequent malignancy (18 patients, 36%). The overall incidence of reported complications was 38%. The most common complications were infections and thromboembolic events, each with an incidence of 10 %. The malposition and disconnection of the port-a-cath were in second place, each with an incidence of 6%.

CONCLUSION

Insertion of the CVC carries the possibility of serious complications (thrombosis, infections, occlusions). However, correct implantation and handling performed by experienced and trained surgical and other medical staff significantly decrease the incidence of these complications. The use of the CVC has greatly improved the quality of life and also decreased the morbidity and mortality of the cancer patients in our study.

摘要

目的

对恶性疾病患者进行多学科治疗需要足够的静脉通路,以便安全地进行化疗、输血及血液制品输注、抗生素使用、补液和全胃肠外营养。中心静脉导管(CVC)的置入、使用及维护可能会伴随多种并发症。

方法

本研究回顾性纳入了50例癌症患者。必须的纳入标准是植入了用于化疗给药的输液港式CVC。本研究纳入了2001年至2012年期间置入导管的患者。

结果

患者中位年龄为44岁(范围28 - 68岁)。35例患者(70%)为女性,15例(30%)为男性。输液港使用时间为1至40个月(平均16.8±9个月)。乳腺癌是最常见的恶性肿瘤(18例,36%)。报告的并发症总发生率为38%。最常见的并发症是感染和血栓栓塞事件,发生率均为10%。输液港位置不当和脱节并列第二,发生率均为6%。

结论

CVC置入存在发生严重并发症(血栓形成、感染、堵塞)的可能性。然而,由经验丰富且经过培训的外科及其他医务人员进行正确的植入和操作可显著降低这些并发症的发生率。在我们的研究中,CVC的使用极大地改善了癌症患者的生活质量,同时也降低了其发病率和死亡率。

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