Zenk W, Winkelmann H, Wagner T
Zahn Mund Kieferheilkd Zentralbl. 1989;77(2):161-6.
In normal morphogenesis age-dependent and regional differences in the surface structure of epithelial cells appear, whereas in teratogenesis no qualitative changes can be observed. During the horizontal adjustment of the palatal shelves the pronounced marking of the cellular borders with microvilli has disappeared. The reduced number of microvilli in the subsequent phase of adhesion might affect the cell-cell identification and thus disturb the further cell differentiation.
在正常形态发生过程中,上皮细胞表面结构会出现年龄依赖性和区域差异,而在致畸过程中则未观察到质性变化。在腭突的水平调整过程中,微绒毛对细胞边界的明显标记消失了。在随后的黏附阶段微绒毛数量减少可能会影响细胞间识别,从而干扰进一步的细胞分化。