Chumpathong Saowapark, Sirithaweesit Chuleeporn, Pechpaisit Nuchsaroch, Suraseranivongse Suwannee, von Bormann Benno, Titapant Vitaya, Parakkamodom Sudta
J Med Assoc Thai. 2014 Jul;97(7):730-5.
Evaluate the CARPREG score in predicting cardiac, obstetric, and neonatal complications in pregnant women with heart disease.
This was a retrospective study between 2002 and 2011 at a tertiary care center and included 175 pregnant women with heart disease. Maternal and neonatal outcomes were assessed using Cardiac in Pregnancy Score (CARPREG), which included NYHA-class, systolic ejection fraction, left ventricular obstruction, and history of cardiac events.
Rheumatic heart disease (n = 116, 66.3%) was the predominant cardiac problem. CARPREG score was 0, 1, > 1 in 65.1%, 24.6%, and 10.3% pregnancies, respectively. Maternal cardiac events occurred in 27.4%. CARPREG score > or = 1 was associated with an increased rate of cardiac events [odds ratio (OR) 6.76, 95% confidence interval (CI) 3.26 to 14.01]. Fetal complications occurred 24.4%. Neonatal birth weight < 2,500 g was associated with CARPREG score > or = 1 (OR 2.57, 95% CI 1.29 to 5.11).
Maternal cardiac events can be predicted using CARPREG risk index. In Thai population, rheumatic heart disease was the most frequent form of cardiac problems in pregnant women.
评估CARPREG评分对预测心脏病孕妇的心脏、产科及新生儿并发症的作用。
这是一项于2002年至2011年在一家三级护理中心开展的回顾性研究，纳入了175例心脏病孕妇。使用妊娠心脏评分（CARPREG）评估孕产妇和新生儿结局，该评分包括纽约心脏协会（NYHA）分级、收缩期射血分数、左心室梗阻及心脏事件史。
风湿性心脏病（n = 116，66.3%）是主要的心脏问题。CARPREG评分在65.1%、24.6%和10.3%的妊娠中分别为0、1、>1。孕产妇心脏事件发生率为27.4%。CARPREG评分>或=1与心脏事件发生率增加相关[比值比（OR）6.76，95%置信区间（CI）3.26至14.01]。胎儿并发症发生率为24.4%。新生儿出生体重<2500 g与CARPREG评分>或=1相关（OR 2.57，95%CI 1.29至5.11）。
可使用CARPREG风险指数预测孕产妇心脏事件。在泰国人群中，风湿性心脏病是孕妇最常见的心脏问题类型。
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