Dorn Research Institute, Arnold School of Public Health, William Jennings Bryan Dorn Veterans Affairs Hospital, University of South Carolina, Columbia, South Carolina, USA.
Research Division, Research Compliance Department, Palmetto Health, Columbia, South Carolina, USA.
Kidney Int. 2014 Oct;86(4):673-5. doi: 10.1038/ki.2014.164.
Although the goal glomerular filtration rate (GFR) for chronic dialysis initiation is currently above 5 ml/min per 1.73 m(2), there is no convincing evidence that patients will benefit from this approach. With close follow-up of advanced chronic kidney disease patients, aiming to start dialysis at an estimated GFR (eGFR) less than 5 ml/min per 1.73 m(2) may result in the avoidance of potentially unnecessary end-of-life dialysis and could result in significant dialysis-free time for a large segment of the world's future dialysis population.
尽管目前慢性透析起始的目标肾小球滤过率（GFR）高于 5ml/min/1.73m(2)，但并没有令人信服的证据表明患者将从中受益。通过对晚期慢性肾脏病患者进行密切随访，将目标 GFR（eGFR）设定在低于 5ml/min/1.73m(2)以下开始透析，可能避免潜在的不必要的终末期透析，并为世界上未来大部分透析人群带来显著的无透析时间。
