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增殖性糖尿病视网膜病变联合手术与序贯手术的比较:单术者研究

Comparison of combined and sequential surgery for proliferative diabetic retinopathy: a single surgeon study.

作者信息

Yang Ye, Zhang Jie, Yan Hong

机构信息

Department of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China; Chinese People's Liberation Army 451 Hospital, Xi'an, Shaanxi, China.

Department of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.

出版信息

PLoS One. 2014 Sep 30;9(9):e108933. doi: 10.1371/journal.pone.0108933. eCollection 2014.

Abstract

PURPOSE

To compare the results of combined and consecutive surgeries to treat proliferative diabetic retinopathy and cataract.

METHODS

Retrospective comparative study. Forty-one patients with proliferative diabetic retinopathy (PDR) were enrolled. Twenty-nine eyes for the combined surgery group and twelve eyes for the sequential group were included. All surgeries were performed by one surgeon. Phacoemulsification was performed using a clear cornea incision. The vitrectomy was performed using a 20-gauge vitreous cutter.

RESULTS

The best corrected visual acuity (BCVA) and intra- and post-operative complications were the main outcome measures. In the combined surgery group, the BCVA increased in 18 (62.1%) eyes, while eight (27.6%) eyes remained stable and three (10.3%) eyes decreased. Postoperative complications included fibrinous exudation in nine eyes, macular edema in three eyes and vitreous hemorrhage in three eyes. In the sequential surgery group, the BCVA increased in seven (58.3%) eyes, remained the same in four (33.3%) eyes and was reduced in one (8.3%) eye. Postoperative complications included macular edema in two eyes, neovascular glaucoma in two eyes and vitreous hemorrhage in one eye.

CONCLUSIONS

Both combined and sequential surgeries are safe and effective for treating PDR and cataracts. The combined surgery had a higher incidence of fibrinous exudation.

摘要

目的

比较联合手术和分期手术治疗增殖性糖尿病视网膜病变和白内障的效果。

方法

回顾性对照研究。纳入41例增殖性糖尿病视网膜病变(PDR)患者。联合手术组29眼,分期手术组12眼。所有手术均由同一位外科医生进行。采用透明角膜切口行超声乳化术。使用20G玻璃体切割器行玻璃体切除术。

结果

主要观察指标为最佳矫正视力(BCVA)以及术中及术后并发症。联合手术组中,18只眼(62.1%)的BCVA提高,8只眼(27.6%)保持稳定,3只眼(10.3%)下降。术后并发症包括9只眼出现纤维蛋白渗出、3只眼出现黄斑水肿和3只眼出现玻璃体出血。分期手术组中,7只眼(58.3%)的BCVA提高,4只眼(33.3%)保持不变,1只眼(8.3%)下降。术后并发症包括2只眼出现黄斑水肿、2只眼出现新生血管性青光眼和1只眼出现玻璃体出血。

结论

联合手术和分期手术治疗PDR和白内障均安全有效。联合手术纤维蛋白渗出的发生率较高。

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