Rivas-Aguiño P, García-Amaris R A, Berrocal M H, Sánchez J G, Rivas A, Arévalo J F
Servicio de Retina y Vítreo, Clínica Oftalmológica Centro Caracas, Caracas, Venezuela.
Arch Soc Esp Oftalmol. 2009 Jan;84(1):31-8. doi: 10.4321/s0365-66912009000100005.
To report the intra-and postoperative complications and visual acuity outcomes in pars plana vitrectomy (PPV), phacoemulsification and intraocular lens (IOL) implantation in patients with cataract and proliferative diabetic retinopathy (PDR). A comparison of the combined versus two-step surgical approach is given.
Retrospective uncontrolled interventional clinical trial. Forty-eight eyes of 48 consecutive patients with PDR were included. Twenty-eight (58.3%) eyes with combined surgery and 20 (41.7%) eyes with sequential surgery were analyzed.
Postoperative follow-up time was between 6 and 63 months (mean: 18 months). 1) Combined surgery: Preoperative best-corrected visual acuity (BCVA) ranged from 20/200 to hand motions, and postoperative BCVA ranged from 20/30 to hand motions. BCVA improved in 17 eyes (60.7%), while in 7 (25%) eyes there was no change (> or =2 ETDRS lines) in VA, and in 4 (14.3%) eyes BCVA decreased. Postoperative complications included vitreous hemorrhage (VH) in 10 (35.7%) eyes, and fibrinous exudation in 9 (32.1%) eyes. 2) Two-step surgery: Preoperative BCVA ranged from 10/200 to light perception, and from 20/40 to light perception in the postoperative period. Best-corrected visual acuity improved in 15 (75%) eyes, remained the same in 4 (20%) eyes, and decreased in 1 (5%) eye. Postoperative complications included fibrinous exudation in 6 (30%) eyes, and VH in 3 (15%) eyes.
Combined PPV, phacoemulsification and IOL implantation as well as the two-step procedure are safe and effective for the management of cataract in PDR. Sequential surgery could be advantageous to BCVA outcomes by minimizing postoperative VH, which is significantly more frequent after combined surgery.
报告白内障合并增殖性糖尿病视网膜病变(PDR)患者行玻璃体切割术(PPV)、超声乳化白内障吸除联合人工晶状体(IOL)植入术的术中及术后并发症以及视力结果。对联合手术与两步手术方法进行比较。
回顾性非对照干预性临床试验。纳入48例连续PDR患者的48只眼。分析28只(58.3%)行联合手术的眼和20只(41.7%)行序贯手术的眼。
术后随访时间为6至63个月(平均:18个月)。1)联合手术:术前最佳矫正视力(BCVA)范围为20/200至手动,术后BCVA范围为20/30至手动。17只眼(60.7%)的BCVA提高,7只眼(25%)的视力无变化(≥2条ETDRS线),4只眼(14.3%)的BCVA下降。术后并发症包括10只眼(35.7%)发生玻璃体积血(VH),9只眼(32.1%)出现纤维蛋白渗出。2)两步手术:术前BCVA范围为10/200至光感,术后为20/40至光感。15只眼(75%)的最佳矫正视力提高,4只眼(20%)保持不变,1只眼(5%)下降。术后并发症包括6只眼(30%)出现纤维蛋白渗出,3只眼(15%)发生VH。
PPV、超声乳化白内障吸除联合IOL植入的联合手术以及两步手术方法对于治疗PDR合并白内障是安全有效的。序贯手术通过减少术后VH可能对BCVA结果更有利,联合手术后VH的发生率明显更高。