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[高血压性左心室肥厚的程控心室刺激数据]

[Data of programmed ventricular stimulation in left ventricular hypertrophy of hypertensive origin].

作者信息

Clémenty J, Coste P, Dallocchio M, Bricaud H

机构信息

Service de Cardiologie, Hôpital du Haut-Lévèque, Passac.

出版信息

Ann Cardiol Angeiol (Paris). 1989 Jun;38(6):297-303.

PMID:2527015
Abstract

Various studies have established the increase of sudden death in hypertensive patients with left ventricular hypertrophy (LVH). In order to specify its most important factors, an electrophysiological study consisting of Holter recording (HR) and programmed ventricular stimulation (PVS), was performed in 24 patients with hypertension: 12 with LVH and 12 without LVH, on ultrasonography. In all patients, coronary angiography was normal. The results are the following: 1) LVH increases the ventricular vulnerability, this arrhythmogenic substrate and its stability are explored by PVS; 2) HR and PVS are not correlated, therefore HR does not explore the arrhythmogenic substrate of LVH, but rather the potential triggering factors of severe rhythm disorders; 3) it has not been possible to evaluate the role of the autonomous nervous system in this study; 4) finally, a significant correlation was found between the degree of anatomical hypertrophy of the LV and the duration of the interval AH.

摘要

多项研究证实,左心室肥厚(LVH)的高血压患者猝死风险增加。为明确其最重要的因素,对24例高血压患者进行了一项电生理研究,包括动态心电图记录(HR)和程控心室刺激(PVS):其中12例经超声心动图检查有LVH,12例无LVH。所有患者冠状动脉造影均正常。结果如下:1)LVH增加心室易损性,通过PVS探究这种致心律失常基质及其稳定性;2)HR与PVS不相关,因此HR不能探究LVH的致心律失常基质,而是严重节律紊乱的潜在触发因素;3)本研究无法评估自主神经系统的作用;4)最后,发现LV解剖学肥厚程度与AH间期持续时间之间存在显著相关性。

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