Boot R, Angulo A F, Walvoort H C
Department of Animal Supply, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands.
Lab Anim. 1989 Jul;23(3):203-7. doi: 10.1258/002367789780810626.
Clostridium difficile (toxin) associated typhlitis was diagnosed in untreated barrier-maintained specific pathogen free guineapigs. It resembled the pathological lesions of antibiotic induced enterocolitis. The possible role of limited colonization resistance to C. difficile provided by mouse enteric microflora in the pathogenesis of the disease is discussed.
在未经治疗的屏障饲养的无特定病原体豚鼠中诊断出艰难梭菌（毒素）相关性盲肠炎。它类似于抗生素诱导的小肠结肠炎的病理病变。讨论了小鼠肠道微生物群对艰难梭菌有限的定植抗性在该疾病发病机制中的可能作用。
