Broussolle Emmanuel, Gobert Florent, Danaila Teodor, Thobois Stéphane, Walusinski Olivier, Bogousslavsky Julien
Centre de Neurosciences Cognitives, Service de Neurologie C, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Université Claude Bernard Lyon I, Lyon, France.
Front Neurol Neurosci. 2014;35:181-97. doi: 10.1159/000360242. Epub 2014 Jun 26.
This historical review presents the advances made mostly during the last 200 years on the description, concepts, theories, and (more specifically) cure of patients suffering from hysteria, a still obscure entity. The denomination of the syndrome has changed over time, from hysteria (reinvestigated by Paul Briquet and Jean-Martin Charcot) to pithiatism (Joseph Babinski), then to conversion neurosis (Sigmund Freud), and today functional neurological disorders according to the 2013 American Neurological Association DSM-5 classification. The treatment was renewed in the second half of the 19th century in Paris by Paul Briquet and then by Jean-Martin Charcot. Hysterical women, who represented the great majority of cases, were cured by physical therapy (notably physio-, hydro-, and electrotherapy, and in some cases ovary compression) and 'moral' therapies (general, causal therapy, rest, isolation, hypnosis, and suggestion). At the turn of the 19th and 20th centuries, psychotherapy, psychoanalysis, and persuasion were established respectively by Pierre Janet, Sigmund Freud, and Joseph Babinski. During World War I, military forces faced a large number of posttrauma neurosis cases among soldiers (named the 'Babinski-Froment war neurosis' and Myers 'shell shock', in the French and English literature, respectively). This led to the use of more brutal therapies in military hospitals, combining electrical shock and persuasion, particularly in France with Clovis Vincent and Gustave Roussy, but also in Great Britain and Germany. After World War I, this method was abandoned and there was a marked decrease in interest in hysteria for a long period of time. Today, the current treatment comprises (if possible intensive) physiotherapy, together with psychotherapy, and in some cases psychoanalysis. Antidepressants and anxiolytics may be required, and more recently cognitive and behavioral therapy. Repetitive transcranial magnetic stimulation is a new technique under investigation which may be promising in patients presenting with motor conversion syndrome (motor deficit or movement disorder). Functional neurological disorders remain a difficult problem to manage with frequent failures and chronic handicapping evolution. This emphasizes the need for therapeutic innovations in the future.
这篇历史综述介绍了主要在过去200年里,在对癔症患者的描述、概念、理论以及(更具体地)治疗方面所取得的进展。癔症这一病症至今仍较为模糊。该综合征的命名随时间不断变化,从癔症(由保罗·布里凯和让 - 马丁·沙可重新研究)到意病(约瑟夫·巴宾斯基),再到转换性神经症(西格蒙德·弗洛伊德),而如今根据2013年美国神经学会《精神疾病诊断与统计手册》第5版的分类为功能性神经障碍。19世纪下半叶,保罗·布里凯继而让 - 马丁·沙可在巴黎开启了对癔症治疗方法的革新。癔症患者占大多数病例,她们通过物理治疗(尤其是物理治疗、水疗和电疗,某些情况下还有卵巢压迫)以及“道德”疗法(一般疗法、病因疗法、休息、隔离、催眠和暗示)得以治愈。在19世纪与20世纪之交,皮埃尔·雅内、西格蒙德·弗洛伊德和约瑟夫·巴宾斯基分别确立了心理治疗、精神分析和说服疗法。第一次世界大战期间,军队在士兵中面临大量创伤后神经症病例(在法语文献中称为“巴宾斯基 - 弗罗芒战争神经症”,在英语文献中称为迈尔斯的“炮弹休克症”)。这导致在军事医院采用更为粗暴的疗法,将电击和说服相结合,尤其在法国有克洛维斯·文森特和古斯塔夫·鲁西这样的情况,在英国和德国也存在。第一次世界大战后,这种方法被摒弃,并且在很长一段时间里对癔症的关注度显著下降。如今,当前的治疗方法包括(如有可能进行强化的)物理治疗,同时辅以心理治疗,某些情况下还包括精神分析。可能需要使用抗抑郁药和抗焦虑药,最近还包括认知行为疗法。重复经颅磁刺激是一项正在研究的新技术,对于患有运动转换综合征(运动功能缺损或运动障碍)的患者可能颇具前景。功能性神经障碍仍然是一个难以处理的问题,经常治疗失败且病情会发展为慢性残疾。这凸显了未来治疗创新的必要性。