Malekinejad Mohsen, Mohraz Minoo, Razani Nooshin, Akbari Gholamreza, McFarland Willi, Khairandish Parastoo, Malekafzali Housien, Gouya Mohammad M, Zarghami Asieh, Rutherford George W
Institute for Health Policy Studies, University of California, 3333 California Street, Suite 265, San Francisco, CA, 94118, USA,
AIDS Behav. 2015 Mar;19(3):440-9. doi: 10.1007/s10461-014-0904-y.
Iran is facing unprecedented dual drug use and HIV epidemics. We conducted a cross-sectional survey to obtain HIV prevalence and risk behavior data from injection drug users (IDU) in Tehran. We used respondent-driven sampling (RDS) to recruit IDU through successive waves starting with 24 "seeds," conducted anonymous face-to-face interviews and HIV testing and counseling, and used RDSAT to adjust data. During 44 weeks, 1,726 study referral coupons resulted in 645 (37 %) IDU referrals, of whom 548 (85 %) were enrolled. From those enrolled, 84 % were incarcerated, 47 % employed, 55 % single, 27 % under 30 years of age, and 26 % homeless. The adjusted HIV prevalence was 26.6 % (95 % confidence interval 21.3-32.1), and was higher among certain IDU subgroups (e.g., those who sharing injection paraphernalia). Our estimates of HIV prevalence were higher than some other estimates; however, repeated surveys using similar methodology are needed to monitor the trend of HIV epidemic over time.
伊朗正面临前所未有的双重药物使用和艾滋病流行问题。我们开展了一项横断面调查,以获取德黑兰注射吸毒者(IDU)的艾滋病毒流行率和风险行为数据。我们采用应答者驱动抽样(RDS)方法,从24名“种子”开始,通过连续多轮招募注射吸毒者,进行匿名面对面访谈、艾滋病毒检测和咨询,并使用RDSAT对数据进行调整。在44周内,1726张研究转诊优惠券带来了645名(37%)注射吸毒者转诊,其中548名(85%)被纳入研究。在纳入的人员中,84%被监禁,47%就业,55%单身,27%年龄在30岁以下,26%无家可归。调整后的艾滋病毒流行率为26.6%(95%置信区间21.3 - 32.1),在某些注射吸毒者亚组中更高(例如,那些共用注射器具的人)。我们对艾滋病毒流行率的估计高于其他一些估计;然而,需要使用类似方法进行重复调查,以监测艾滋病毒流行随时间的趋势。