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致密性骨发育不全症与一位艺术家的诞生。

Pycnodysostosis and the making of an artist.

作者信息

Hodder Angus, Huntley Catherine, Aronson Jeffrey K, Ramachandran Manoj

机构信息

Centre for Orthopaedics, The Royal London and Barts and The London Children's Hospitals, Barts Health NHS Trust, Whitechapel Road, Whitechapel, London E1 1BB, UK.

Green Templeton College, Woodstock Road, Oxford OX2 6HG, UK.

出版信息

Gene. 2015 Jan 15;555(1):59-62. doi: 10.1016/j.gene.2014.09.055. Epub 2014 Sep 30.

DOI:10.1016/j.gene.2014.09.055
PMID:25280595
Abstract

Henri de Toulouse-Lautrec, a 19th century artist celebrated for his depictions of the Moulin Rouge and Parisian nightlife, suffered from an unknown disorder. His symptoms were not only rare, but also difficult to determine. Both during his lifetime and following his death potential diagnoses have proved controversial, including the most popularly supported suggestion of pycnodysostosis. Addressing the ongoing debate of Toulouse-Lautrec's diagnosis, this article reconsiders the evidence. It summarises multiple perspectives and draws on more recent medical research, while acknowledging that the available sources are often unreliable. Ultimately, while there may be no definitive solution to the mystery of Toulouse-Lautrec's diagnosis, it is possible to draw one conclusion. Observing its impact on his life and work, it is clear that the condition formed the foundation of Toulouse-Lautrec's artistic career, shaping the way he perceived the world and defining the artworks that are now so widely admired.

摘要

亨利·德·图卢兹-洛特雷克是一位19世纪的艺术家,以描绘红磨坊和巴黎夜生活而闻名,他患有某种不明疾病。他的症状不仅罕见,而且难以确定。无论是在他生前还是死后,潜在的诊断结果都颇具争议,其中最广为认可的推测是致密性成骨不全症。针对关于图卢兹-洛特雷克诊断的持续争论,本文重新审视了相关证据。它总结了多种观点,并借鉴了最新的医学研究成果,同时承认现有资料往往不可靠。最终,虽然对于图卢兹-洛特雷克的诊断之谜可能没有定论,但可以得出一个结论。观察这种疾病对他生活和作品的影响,很明显这种状况构成了图卢兹-洛特雷克艺术生涯的基础,塑造了他看待世界的方式,并决定了如今广受赞赏的艺术作品。

相似文献

1
Pycnodysostosis and the making of an artist.致密性骨发育不全症与一位艺术家的诞生。
Gene. 2015 Jan 15;555(1):59-62. doi: 10.1016/j.gene.2014.09.055. Epub 2014 Sep 30.
2
Pycnodysostosis: the disease of Henri de Toulouse-Lautrec.致密性骨发育不全症:亨利·德·图卢兹-洛特雷克所患的疾病。
Eur J Orthop Surg Traumatol. 2018 Dec;28(8):1569-1572. doi: 10.1007/s00590-018-2233-8. Epub 2018 May 24.
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Henri Marie Raymond de Toulouse-Lautrec-Montfa (1864-1901): artistic genius and medical curiosity.
J Med Biogr. 2013 Feb;21(1):19-25. doi: 10.1258/jmb.2011.011069.
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Pycnodysostosis; A Rare Disease Case Report.致密性骨发育不全症;罕见病例报告
J Ayub Med Coll Abbottabad. 2022 Jan-Mar;34(1):216-219. doi: 10.55519/JAMC-01-10336.
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Pycnodysostosis with unusual findings: a case report.伴有异常表现的致密性骨发育不全:一例报告
Cases J. 2009 Jul 23;2:6544. doi: 10.4076/1757-1626-2-6544.
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[Pycnodysostosis in the radiographic picture (Toulouse Lautrec's disease--3 new cases)].[影像学表现中的致密性骨发育不全(图卢兹·劳特雷克病——3例新病例)]
Fortschr Geb Rontgenstr Nuklearmed. 1973 Mar;118(3):298-305.
7
[Henri de Toulouse-Lautrec's illness].[亨利·德·图卢兹-洛特雷克的病症]
Sem Hop. 1957 Jul 10;33(41):2697.
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Linkage of pycnodysostosis to chromosome 1q21 by homozygosity mapping.通过纯合性定位将致密性骨发育不全定位到1号染色体长臂2区1带
Nat Genet. 1995 Jun;10(2):235-7. doi: 10.1038/ng0695-235.
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Pycnodysostosis: Toulouse-Lautrec's and Aesop's disease?致密性成骨不全症:图卢兹 - 洛特雷克与伊索的病症?
Hormones (Athens). 2002 Oct-Dec;1(4):260-2.
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Toulouse-Lautrec's diagnosis.
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引用本文的文献

1
Genetic and Molecular Evaluation: Reporting Three Novel Mutations and Creating Awareness of Pycnodysostosis Disease.遗传与分子评估:报告三个新突变并提高对先天性成骨不全症的认识。
Genes (Basel). 2021 Sep 29;12(10):1552. doi: 10.3390/genes12101552.
2
Disturbed remodeling and delayed fracture healing in pediatric pycnodysostosis patients.小儿致密性骨发育不全患者的骨重塑紊乱与骨折愈合延迟
J Orthop. 2019 Apr 15;16(5):373-377. doi: 10.1016/j.jor.2019.03.022. eCollection 2019 Sep-Oct.
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[Pycnodysostosis: about a case].[致密性骨发育不全症:关于一例病例]
Pan Afr Med J. 2018 Oct 8;31:93. doi: 10.11604/pamj.2018.31.93.8388. eCollection 2018.
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Art in Science: The Artist and The Disease: The Exemplary Cases of Renoir and Toulouse-Lautrec.科学中的艺术:艺术家与疾病:雷诺阿和图卢兹 - 劳特累克的典型案例
Clin Orthop Relat Res. 2017 Oct;475(10):2376-2381. doi: 10.1007/s11999-017-5458-7. Epub 2017 Aug 7.