Lymphology. 2014 Jun;47(2):51-64.
It is well documented that resistance exercise can be performed by patients with breast cancer-related arm lymphedema. The aim of this pilot study was to evaluate the feasibility and safety of a 12-week self-administered weight lifting program for arm and shoulder, and its influence on arm lymphedema status, upper extremity muscle strength, and disability. Twenty-three patients with breast cancer-related arm lymphedema performed the program 3 times/week. The weight resistance levels were individually adjusted for shoulder flexion and adduction, and elbow extension and flexion corresponding to a repetition range of 8-12 repetition maximum. A log book was used to evaluate adherence to the program, wearing of compression sleeve and perceived exertion. Measurements were performed before a 2-week control period without intervention, and before and after intervention, and with arm volume measurements every fortnight to check for adverse events. Results revealed no significant changes during the control period. Adherence to the intervention program was excellent, and two adverse events were registered during the first weeks. After intervention, an increase of shoulder and arm strength (measured by an isometric muscle strength device) was found in all exercises (p = 0.001-0.003). A reduction of excess volume was shown, in ml (p = 0.03) and percentage (p = 0.005), measured by water displacement method. A tendency towards reduction (p = 0.07) of fat tissue in the upper arm (n = 10) in both arms was found measured by MRI. In this pilot study, we concluded that a home-based weight-lifting program performed by patients with breast cancer-related arm lymphedema is feasible and safe providing that the program includes regular follow-up for safety.
有大量文献证明，患有乳腺癌相关上肢淋巴水肿的患者可以进行抗阻运动。本研究旨在评估为期 12 周的自我管理的上肢和肩部举重方案的可行性和安全性，及其对上肢淋巴水肿状况、上肢肌肉力量和残疾的影响。23 例患有乳腺癌相关上肢淋巴水肿的患者每周进行 3 次该方案。根据 8-12 次重复最大量的重复范围，针对肩前屈和内收、肘伸展和屈曲，为每位患者单独调整重量阻力水平。日志用于评估对方案的依从性、压缩袖套的佩戴情况和感知用力情况。在没有干预的 2 周对照期之前、干预之前和之后进行测量，并每两周进行一次手臂体积测量，以检查不良事件。结果显示对照期内无显著变化。干预方案的依从性极好，并且在最初几周内记录了 2 起不良事件。干预后，所有运动（通过等速肌力仪测量）的肩和臂力量均增加（p = 0.001-0.003）。通过排水量法测量，多余体积（以毫升为单位，p = 0.03）和百分比（p = 0.005）均减少。通过 MRI 对 10 例患者双侧上肢的上臂脂肪组织（n = 10）进行测量，发现其有减少的趋势（p = 0.07）。在这项初步研究中，我们得出结论，患有乳腺癌相关上肢淋巴水肿的患者可以在家中进行抗阻运动，方案包括定期随访以确保安全性，该方案是可行且安全的。
