Lozano F S, March J R, González-Porras J R, Carrasco E, Lobos J M, Ros E
Hospital Universitario de Salamanca and IBSAL, Salamanca, Spain.
Int J Clin Pract. 2014 Dec;68(12):1478-82. doi: 10.1111/ijcp.12499. Epub 2014 Oct 4.
The Ankle-Brachial Index (ABI) makes it possible to identify patients with peripheral artery disease (PAD). Intermittent claudication (IC) is the first major symptom of PAD, although many patients with an ABI ≤ 0.9 do not exhibit IC, and the range of ABI among those who do have IC is very variable. This study evaluates the correlation between ABI and the perception (symptomatology) of claudicant patients.
An observational, cross-sectional and multicentre, study of 920 patients with IC. Clinical history, ABI, Walking Impairment Questionnaire (WIQ) and European Quality of Life Questionnaire (EQ-5D) were recorded. Associations were analysed using Spearman's correlation coefficient.
The mean ABI of the series was 0.63 (SD = 0.19). The mean WIQ-distance was 34.07 (SD = 26.77), values being smaller for lower ABI values (r = 0.343, p < 0.001). The mean EQ-5D score of the series was 0.58 (SD = 0.21), also showing lower values as the ABI decreased (r = 0.278, p < 0.001). The correlations of WIQ and EQ-5D with ABI were statistically significant in both cases, but always less than 0.400 (between 0.278 and 0.343).
The correlations of ABI with the questionnaires of walking capacity and quality of life are weak. For this reason, although in clinical practice the ABI of CI patients is commonly measured, decisions should not be taken during the development of IC exclusively on the basis of the ABI.
踝臂指数(ABI)有助于识别外周动脉疾病(PAD)患者。间歇性跛行(IC)是PAD的首个主要症状,不过许多ABI≤0.9的患者并未表现出IC症状,而且有IC症状患者的ABI范围差异很大。本研究评估ABI与跛行患者的感知(症状学)之间的相关性。
一项针对920例IC患者的观察性、横断面多中心研究。记录临床病史、ABI、步行障碍问卷(WIQ)和欧洲生活质量问卷(EQ-5D)。使用Spearman相关系数分析相关性。
该系列研究的平均ABI为0.63(标准差=0.19)。WIQ距离的平均值为34.07(标准差=26.77),ABI值越低,该值越小(r=0.343,p<0.001)。该系列研究的平均EQ-5D评分为0.58(标准差=0.21),同样随着ABI降低而呈现更低的值(r=0.278,p<0.001)。WIQ和EQ-5D与ABI的相关性在两种情况下均具有统计学意义,但始终小于0.400(在0.278至0.343之间)。
ABI与步行能力问卷和生活质量问卷之间的相关性较弱。因此,尽管在临床实践中通常会测量IC患者的ABI,但在IC发展过程中不应仅基于ABI做出决策。