Bourgeois Blaise F D, Douglass Laurie M, Sankar Raman
Harvard Medical School, Children's Hospital, Boston, Massachusetts, U.S.A.
Epilepsia. 2014 Sep;55 Suppl 4:4-9. doi: 10.1111/epi.12567.
Lennox-Gastaut syndrome (LGS) is a severe epileptic encephalopathy that shares many features and characteristics of other treatment-resistant childhood epilepsies. Accurate and early diagnosis is essential to both prognosis and overall patient management. However, accurate diagnosis of LGS can be clinically challenging. This article summarizes key characteristics of LGS and areas of overlap with other childhood epilepsies. Drawing upon input from a committee of established LGS experts convened in June 2012 in Chicago, Illinois, the authors highlight key diagnostic tests for making the differential diagnosis and propose a diagnostic scheme for people with suspected LGS.
伦诺克斯-加斯托综合征（LGS）是一种严重的癫痫性脑病，具有许多其他难治性儿童癫痫的特征。准确的早期诊断对于预后和患者的整体管理至关重要。然而，LGS的准确诊断在临床上可能具有挑战性。本文总结了LGS的关键特征以及与其他儿童癫痫的重叠领域。作者借鉴了2012年6月在伊利诺伊州芝加哥召集的LGS专家委员会的意见，强调了进行鉴别诊断的关键诊断测试，并为疑似LGS患者提出了一种诊断方案。
