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在睾丸扭转实验大鼠模型中,用电针样经皮神经刺激改善睾丸血流。

Improving testicular blood flow with electroacupuncture-like percutaneous nerve stimulation in an experimental rat model of testicular torsion.

作者信息

Acar Omer, Esen Tarik, Colakoglu Bulent, Camli Mehmet Fatih, Cakmak Yusuf Ozgur

机构信息

Department of Urology, VKF American Hospital, Istanbul, Turkey.

Department of Urology, School of Medicine, Koc University, Istanbul, Turkey.

出版信息

Neuromodulation. 2015 Jun;18(4):324-8; discussion 328. doi: 10.1111/ner.12246. Epub 2014 Oct 6.

DOI:10.1111/ner.12246
PMID:25284428
Abstract

INTRODUCTION

The purpose of this study was to determine the blood-flow-enhancing effect of electroacupuncture (EA) in an experimental rat model of testicular torsion.

METHODS

At the first stage, 3D color Doppler ultrasound (3D-CDUS) scans were made to detect baseline perfusion of each testicle in 12 male albino Wistar rats. Then, the left testicles of all rats were twisted 180° clockwise, and 3D-CDUS recordings were repeated. In the next step, 10-Hz EA was applied for 5 min over the T13 and L4 dermatome territories in the study group of six rats. In the control group of six rats, acupuncture needles were inserted in the same manner, but EA was not applied. Baseline, posttorsion, and postintervention (EA and manual needling) 3D-CDUS perfusion recordings were interpreted as volumetric data, and group comparisons were performed.

RESULTS

After EA, we observed statistically significant perfusion improvements in both the ipsilateral torsed and contralateral nontorsed testicles. In the control group, testicular perfusion did not show a significant change after manual needling.

CONCLUSION

EA can improve testicular blood flow bilaterally in a rat model of unilateral testicular torsion at 180°.

摘要

引言

本研究的目的是在睾丸扭转实验大鼠模型中确定电针(EA)的血流增强作用。

方法

在第一阶段,对12只雄性白化Wistar大鼠的每个睾丸进行三维彩色多普勒超声(3D-CDUS)扫描以检测基线灌注。然后,将所有大鼠的左侧睾丸顺时针扭转180°,并重复进行3D-CDUS记录。下一步,对6只大鼠的研究组在T13和L4皮节区域施加10 Hz的电针5分钟。在6只大鼠的对照组中,以相同方式插入针灸针,但不施加电针。将基线、扭转后和干预后(电针和手针)的3D-CDUS灌注记录解释为体积数据,并进行组间比较。

结果

电针后,我们观察到同侧扭转和对侧未扭转睾丸的灌注均有统计学意义的改善。在对照组中,手针后睾丸灌注未显示出显著变化。

结论

在180°单侧睾丸扭转的大鼠模型中,电针可双侧改善睾丸血流。

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