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高龄患者经会阴直肠切除术的临床疗效。

Clinical outcomes of perineal proctectomy among patients of advanced age.

机构信息

1University of Bangkok Metropolis, Bangkok, Thailand 2Division of Colon and Rectal Surgery, University of Minnesota, Minneapolis, Minnesota 3Division of Colon and Rectal Surgery, University of Illinois at Chicago, Chicago, Illinois.

出版信息

Dis Colon Rectum. 2014 Nov;57(11):1298-303. doi: 10.1097/DCR.0000000000000225.

Abstract

BACKGROUND

Rectal prolapse occurs primarily in older patients who often have significant comorbidities. With the aging population, increasing numbers of elderly patients are presenting with rectal prolapse. The perineal approach is preferred for these patients because it involves less perioperative risk than an abdominal procedure, but the outcomes of this procedure in elderly patients are unknown.

OBJECTIVE

The aim of this study was to examine whether clinical outcomes after perineal proctectomy are similar among elderly patients versus patients of younger age.

DESIGN

This study was a retrospective review.

SETTING

This study was conducted in mixed academic and private practice; the operations were performed at 16 hospitals.

PATIENTS

Patients who had perineal proctectomy for rectal prolapse from 1994 to 2012 were grouped according to age: <70 (group A), 70 to 79 (group B), 80 to 89 (group C), and ≥90 years (group D).

INTERVENTIONS

Perineal proctectomy with or without concurrent levatorplasty was performed.

MAIN OUTCOME MEASURES

The primary outcomes measured were postoperative complications, recurrence, and survival after perineal proctectomy.

RESULTS

Four hundred patients underwent 518 perineal proctectomies: group A, N = 113; group B, N = 113; group C, N = 208; and group D, N = 84. The immediate and late complication rates were 5.6% and 3.5% and did not vary by age. Recurrence was 22.6% and was significantly different between groups, with the lowest recurrence in group D, 14.3% (p = 0.007). Reoperation after recurrence was less likely in group D. The main type of reoperation was perineal proctectomy (41.5%), but, for group D, recurrence was usually managed nonoperatively (58.3%). Median survival after operation was more than 4 years in the advanced age group.

LIMITATIONS

Retrospective data, which did not allow analysis of patients with rectal prolapse who did not undergo surgery, were used in this study.

CONCLUSIONS

When selected appropriately, patients 90 years of age or older have outcomes similar to younger patients; therefore, age alone should not be a contraindication to surgery. In addition, elderly patients have a median survival of more than 4 years after surgery, so the operative risk can be worth the benefit accrued.

摘要

背景

直肠脱垂主要发生在有明显合并症的老年患者中。随着人口老龄化,越来越多的老年患者出现直肠脱垂。会阴入路是这些患者的首选方法,因为与腹部手术相比,它涉及的围手术期风险更小,但目前尚不清楚这种手术在老年患者中的效果如何。

目的

本研究旨在探讨会阴直肠切除术治疗老年患者与年轻患者的临床效果是否相似。

设计

本研究为回顾性研究。

设置

本研究在混合学术和私人实践中进行;手术在 16 家医院进行。

患者

1994 年至 2012 年间因直肠脱垂接受会阴直肠切除术的患者根据年龄分组:<70 岁(A 组)、70-79 岁(B 组)、80-89 岁(C 组)和≥90 岁(D 组)。

干预措施

行会阴直肠切除术,伴或不伴提肛肌成形术。

主要观察指标

术后并发症、复发和会阴直肠切除术后的生存率。

结果

400 例患者行 518 例会阴直肠切除术:A 组 113 例,B 组 113 例,C 组 208 例,D 组 84 例。即刻和晚期并发症发生率分别为 5.6%和 3.5%,且与年龄无关。复发率为 22.6%,且各组之间差异有统计学意义,D 组复发率最低(14.3%,p = 0.007)。D 组再次手术后再次复发的可能性较低。再次手术的主要类型是会阴直肠切除术(41.5%),但对于 D 组,复发通常采用非手术治疗(58.3%)。手术治疗后中位生存时间超过 4 年。

局限性

本研究使用的是回顾性数据,因此无法分析未接受手术治疗的直肠脱垂患者。

结论

在适当选择的情况下,90 岁或以上的患者与年轻患者的结果相似;因此,年龄本身不应成为手术的禁忌症。此外,老年患者手术后的中位生存时间超过 4 年,因此手术风险的获益是值得的。

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