日本冈山市的室外空气污染与院外心脏骤停
Outdoor air pollution and out-of-hospital cardiac arrest in Okayama, Japan.
作者信息
Yorifuji Takashi, Suzuki Etsuji, Kashima Saori
机构信息
From the Department of Human Ecology (Dr Yorifuji), Graduate School of Environmental and Life Science; Department of Epidemiology (Dr Suzuki), Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Kita-ku; and Department of Public Health and Health Policy (Dr Kashima), Institute of Biomedical and Health Sciences, Hiroshima University, Minami-ku, Hiroshima, Japan.
出版信息
J Occup Environ Med. 2014 Oct;56(10):1019-23. doi: 10.1097/JOM.0000000000000274.
OBJECTIVES
We evaluated the association between short-term exposure to outdoor air pollution and out-of-hospital cardiac arrest in Japan.
METHODS
We studied 558 residents of Okayama, Japan, who visited hospital emergency departments between January 2006 and December 2010 for out-of-hospital cardiac arrest using a time-stratified case-crossover design. We calculated city-representative average concentrations of different air pollutants and examined the association between air pollution and cardiac arrest.
RESULTS
Exposure to air pollution was associated with an elevated risk of cardiac arrest; for example, odds ratios was 1.17 (95% confidence interval, 1.02 to 1.33) per interquartile-range increase in suspended particulate matter concentrations in the previous 48 to 72 hours. We also observed different susceptibilities to suspended particulate matter and ozone exposures by age category.
CONCLUSIONS
Short-term exposure to outdoor air pollution was associated with increased risk of cardiac arrest.
目的
我们评估了日本短期暴露于室外空气污染与院外心脏骤停之间的关联。
方法
我们采用时间分层病例交叉设计，研究了2006年1月至2010年12月期间因院外心脏骤停前往日本冈山医院急诊科就诊的558名居民。我们计算了不同空气污染物的城市代表性平均浓度，并研究了空气污染与心脏骤停之间的关联。
结果
暴露于空气污染与心脏骤停风险升高相关；例如，在前48至72小时内，悬浮颗粒物浓度每增加一个四分位数间距，比值比为1.17（95%置信区间，1.02至1.33）。我们还观察到不同年龄组对悬浮颗粒物和臭氧暴露的易感性不同。
结论
短期暴露于室外空气污染与心脏骤停风险增加相关。
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