Johnston Douglas R
Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio, USA.
Curr Opin Cardiol. 2014 Nov;29(6):542-6. doi: 10.1097/HCO.0000000000000116.
Ongoing efforts to compare percutaneous coronary intervention with coronary bypass surgery for multivessel coronary disease mandate that surgeons reevaluate best practices for coronary surgery in order to maximize long-term outcomes. This review presents recent data for the long-term outcomes of multiple arterial grafting in terms of patient selection, conduit choice, and technical considerations.
Multiple arterial grafting remains poorly utilized, with fewer than 10% of cases receiving more than one arterial graft. Bilateral internal thoracic artery grafting confers superior long-term survival and freedom from reoperation over single thoracic artery with saphenous vein. Use of a second internal thoracic artery graft is advantageous in diabetic patients despite higher risk of sternal wound complications. Routine use of skeletonized grafts and Y or T grafting to allow complete revascularization allows lower early complication rates and better long-term survival. Radial artery grafts confer superior long-term survival compared with saphenous vein grafts and should be considered in patients at high risk for sternal wound complications.
Multiple arterial grafting confers superior long-term outcomes in comparison with single internal thoracic artery grafting and should be considered as the standard of care.
目前正在努力比较经皮冠状动脉介入治疗与冠状动脉旁路移植术治疗多支冠状动脉疾病的效果,这就要求外科医生重新评估冠状动脉手术的最佳做法,以实现长期效果最大化。本综述介绍了在患者选择、血管桥选择和技术考量方面多支动脉血管桥移植长期效果的最新数据。
多支动脉血管桥移植的使用率仍然很低,接受多于一支动脉血管桥移植的病例不到10%。与单支胸廓内动脉加隐静脉移植相比,双侧胸廓内动脉移植能带来更好的长期生存率,且再次手术率更低。尽管胸骨伤口并发症风险较高,但在糖尿病患者中使用第二支胸廓内动脉血管桥是有益的。常规使用骨骼化血管桥以及采用Y形或T形血管桥以实现完全血运重建,可降低早期并发症发生率并提高长期生存率。与隐静脉血管桥相比,桡动脉血管桥能带来更好的长期生存率,对于胸骨伤口并发症高危患者应考虑使用。
与单支胸廓内动脉血管桥移植相比,多支动脉血管桥移植能带来更好的长期效果,应被视为治疗标准。