Metabolism. 1965 Jul;14(7):832-5. doi: 10.1016/0026-0495(65)90011-9.
Total urinary excretion of hydroxyproline has been found to be significantly decreased in adult diabetics and was increased after hypophysectomy for diabetic retinopathy. There was no change in hydroxyproline excretion after the administration of 53 mg. of human growth hormone to one patient with hypopituitarism over a 4 day period.
现已发现,成年糖尿病患者的羟脯氨酸总排泄量明显减少,且糖尿病性视网膜病变行垂体切除术 后其排泄量增加。对 1 例垂体功能减退症患者在 4 天内给予 53 毫克人生长激素后,羟脯氨酸排泄量无变化。