Lakjiri S, Meziane M, Benani A, Harmouch T, Amarti A, Mernissi F-Z
Service de dermatologie, CHU Hassan II, BP 1835, Atlass, Fès, Maroc.
Service de dermatologie, CHU Hassan II, BP 1835, Atlass, Fès, Maroc.
Ann Dermatol Venereol. 2014 Oct;141(10):598-602. doi: 10.1016/j.annder.2014.06.019. Epub 2014 Aug 7.
Fasciitis with eosinophilia (FE), or Shulman syndrome, is a rare disease of unknown origin for which the nosological profile has not been clearly defined. It is clinically characterised by oedema and induration of the limbs with hypereosinophilia. It may be associated with morphea, in which case it carries a poor prognosis, or other diseases, particularly autoimmune conditions. Herein, we report a case of fasciitis associated with eosinophilia, morphea and vitiligo.
A 45-year-old male patient followed up for vitiligo for 20 years had been presenting swelling and induration of the skin on all 4 limbs for the previous 7 months associated with morphea on the trunk. Treatment consisting of systemic corticosteroids and methotrexate was initiated and displayed a certain degree of efficacy.
The association of morphea/fasciitis with eosinophilia is a classical finding; the presence of vitiligo raises the question of possible association between these different disorders.
嗜酸性筋膜炎（FE），即舒尔曼综合征，是一种病因不明的罕见疾病，其疾病分类尚未明确界定。其临床特征为四肢水肿、硬结伴嗜酸性粒细胞增多。它可能与硬斑病相关，这种情况下预后较差，也可能与其他疾病相关，尤其是自身免疫性疾病。在此，我们报告一例伴有嗜酸性粒细胞增多、硬斑病和白癜风的筋膜炎病例。
一名45岁男性患者，白癜风病史20年，此前7个月四肢皮肤出现肿胀和硬结，并伴有躯干硬斑病。开始采用全身糖皮质激素和甲氨蝶呤治疗，显示出一定程度的疗效。
硬斑病/筋膜炎与嗜酸性粒细胞增多相关是一个典型表现；白癜风的存在引发了这些不同疾病之间可能存在关联的问题。
