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关于使用Stata进行荟萃分析的实践操作教程。

A hands-on practical tutorial on performing meta-analysis with Stata.

作者信息

Chaimani Anna, Mavridis Dimitris, Salanti Georgia

机构信息

Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece.

Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece Department of Primary Education, University of Ioannina, Ioannina, Greece.

出版信息

Evid Based Ment Health. 2014 Nov;17(4):111-6. doi: 10.1136/eb-2014-101967. Epub 2014 Oct 6.

Abstract

Statistical synthesis of research findings via meta-analysis is widely used to assess the relative effectiveness of competing interventions. A series of three papers aimed at familiarising mental health scientists with the key statistical concepts and problems in meta-analysis was recently published in this journal. One paper focused on the selection and interpretation of the appropriate model to synthesise results (fixed effect or random effects model) whereas the other two papers focused on two major threats that compromise the validity of meta-analysis results, namely publication bias and missing outcome data. In this paper we provide guidance on how to undertake meta-analysis using Stata, one of the most commonly used software packages for meta-analysis. We address the three topics covered in the previous issues of the journal, focusing on their implementation in Stata using a working example from mental health research.

摘要

通过荟萃分析对研究结果进行统计综合,被广泛用于评估相互竞争的干预措施的相对有效性。最近,该期刊发表了三篇系列论文,旨在让心理健康科学家熟悉荟萃分析中的关键统计概念和问题。其中一篇论文重点讨论了用于综合结果的合适模型(固定效应模型或随机效应模型)的选择和解释,而另外两篇论文则关注损害荟萃分析结果有效性的两个主要威胁,即发表偏倚和缺失结局数据。在本文中,我们提供了关于如何使用Stata进行荟萃分析的指南,Stata是荟萃分析中最常用的软件包之一。我们阐述了该期刊前几期所涵盖的三个主题,并通过心理健康研究的一个实际例子,重点介绍它们在Stata中的实现。

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