Claman H N
Division of Clinical Immunology, University of Colorado Medical Center, Denver, CO 80262, USA.
Immunol Today. 1985 Jun;6(6):192-5. doi: 10.1016/0167-5699(85)90115-X.
Inflamed, fibrotic lesions containing mast cells are characteristic of several clinical disorders and have been noted in graft versus host disease. Here Henry Claman reviews recent insights into the interactions between mast cells, T lymphocytes and fibroblasts which may account for abnormal collagen deposition.
含有肥大细胞的炎症性纤维化病变是几种临床疾病的特征,并且在移植物抗宿主病中也有发现。在此,亨利·克拉曼回顾了关于肥大细胞、T淋巴细胞和成纤维细胞之间相互作用的最新见解,这些相互作用可能是异常胶原沉积的原因。