Mancinella A
Clin Ter. 1989;130(3-4):159-69.
Having briefly analyzed the metabolism of ethanol in the human organism, the author describes hepatocellular damage induced by chronic alcohol abuse in old men. The evidence of great resistance of the senile liver to alcohol-induced damage is stressed as well as histological, biohumoral and clinical features of steatosis, chronic hepatitis, acute hepatitis and cirrhosis. Further, the author discusses the most suitable dietary and pharmacologic measures to be utilized in the above-mentioned phase of the liver disease due to chronic alcohol abuse.
在简要分析了乙醇在人体中的代谢过程后,作者描述了老年男性慢性酒精滥用所导致的肝细胞损伤。强调了老年肝脏对酒精诱导损伤具有高度抵抗力的证据,以及脂肪变性、慢性肝炎、急性肝炎和肝硬化的组织学、生物体液学和临床特征。此外,作者还讨论了在慢性酒精滥用导致的上述肝病阶段应采用的最合适的饮食和药物治疗措施。