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[严重脓毒症和脓毒性休克]

[Severe sepsis and septic shock].

作者信息

Tønnesen Else, Larsen Kim

机构信息

Anæstesiologisk Afdeling, Aarhus Universitetshospital, Nørrebrogade 44, 8000 Aarhus C.

出版信息

Ugeskr Laeger. 2014 Jul 7;176(28):V03130200.

PMID:25292001
Abstract

Sepsis, severe sepsis and septic shock are syndromes. The incidence of sepsis is as high as 35% and with mortality rates in the intensive care unit from 27% to 54% in sepsis and septic shock, respectively. Many new treatments have been tested but only few have been implemented in clinical practise. The treatment of severe sepsis and septic shock is based on the Surviving Sepsis Campaign guidelines developed by an international expert panel. Early diagnosis, optimization of haemodynamics, rapid identification of focus and adequate antibiotic treatment are the most important strategies.

摘要

脓毒症、严重脓毒症和脓毒性休克均为综合征。脓毒症的发病率高达35%,在重症监护病房中,脓毒症和脓毒性休克的死亡率分别为27%至54%。许多新的治疗方法已经过测试,但只有少数在临床实践中得到应用。严重脓毒症和脓毒性休克的治疗基于国际专家小组制定的《拯救脓毒症运动指南》。早期诊断、血流动力学优化、迅速确定感染源以及充分的抗生素治疗是最重要的策略。

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